Santangelo Philip S, Kockler Tobias D, Zeitler Marie-Luise, Knies Rebekka, Kleindienst Nikolaus, Bohus Martin, Ebner-Priemer Ulrich W
Mental mHealth Lab, Karlsruhe Institute of Technology, Karlsruhe, Germany.
Institute of Psychiatric and Psychosomatic Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Borderline Personal Disord Emot Dysregul. 2020 Nov 24;7(1):25. doi: 10.1186/s40479-020-00140-8.
Borderline personality disorder (BPD) is defined by a pervasive pattern of instability. According to prior findings and clinical theories, self-esteem instability and affective instability are key features of BPD. Previous e-diary studies showed that instability in self-esteem is heightened and that it is highly intertwined with affective instability in BPD in comparison to healthy controls (HC). The present study sought to extend these findings by adding symptomatologically remitted BPD patients (BPD-REM), i.e. former patients with BPD who met four or fewer BPD criteria within the past year, as a comparison group.
To examine differences regarding self-esteem instability and affective instability, we used e-diaries for repeatedly collecting data on self-esteem, valence, and tense arousal 12 times a day for four consecutive days while participants underwent their daily life activities. Determining three different state-of-the-art instability indices and applying multilevel analyses, we compared 35 BPD-REM participants with previously reported 60 acute BPD patients (BPD-ACU) and 60 HC.
Our results revealed that self-esteem instability was significantly lower in the BPD-REM compared to the BPD-ACU group, irrespective of the instability index. In contrast, there were no significant differences regarding affective instability between the BPD-REM participants and those in the BPD-ACU group. The comparison between the BPD-REM with the HC indicated both a significantly higher instability in self-esteem as well as significantly heightened affective instability in the BPD-REM participants. Moreover, even though the associations were not significant, we found tentative support for the assumption that affective changes that are accompanied by changes in self-esteem are experienced as more burdensome and negatively impact the quality of life of remitted BPD participants.
This study builds on growing evidence for the importance of self-esteem instability in BPD. Whereas affective instability has been reported in various psychiatric disorders and might indeed constitute a transdiagnostic marker of affective dysregulation, our results indicate that self-esteem instability might be a specific symptom that construes the unique pathology in BPD.
边缘型人格障碍(BPD)的定义是一种普遍存在的不稳定模式。根据先前的研究结果和临床理论,自尊不稳定和情感不稳定是BPD的关键特征。先前的电子日记研究表明,与健康对照组(HC)相比,BPD患者的自尊不稳定程度更高,且与情感不稳定高度交织。本研究试图通过增加症状缓解的BPD患者(BPD-REM),即过去一年内符合四项或更少BPD标准的前BPD患者,作为对照组来扩展这些发现。
为了研究自尊不稳定和情感不稳定的差异,我们使用电子日记,在参与者进行日常生活活动的连续四天里,每天12次重复收集关于自尊、效价和紧张唤醒的数据。通过确定三种不同的最新不稳定指标并应用多层次分析,我们将35名BPD-REM参与者与先前报道的60名急性BPD患者(BPD-ACU)和60名HC进行了比较。
我们的结果显示,无论不稳定指标如何,BPD-REM组的自尊不稳定程度均显著低于BPD-ACU组。相比之下,BPD-REM参与者与BPD-ACU组参与者在情感不稳定方面没有显著差异。BPD-REM与HC的比较表明,BPD-REM参与者的自尊不稳定程度显著更高,情感不稳定程度也显著增强。此外,尽管相关性不显著,但我们初步支持这样的假设,即伴随自尊变化的情感变化会给缓解期的BPD参与者带来更大负担,并对其生活质量产生负面影响。
本研究基于越来越多的证据,证明自尊不稳定在BPD中的重要性。虽然情感不稳定在各种精神疾病中都有报道,并且可能确实构成情感失调的跨诊断标志物,但我们的结果表明,自尊不稳定可能是一种特定症状,构成了BPD独特的病理学特征。