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一名急性期无持续性高血压的低钠血症性高血压综合征儿科患者:病例报告及文献复习

A pediatric patient with hyponatremic hypertensive syndrome without persistent hypertension in acute phase: A case report and review of literature.

作者信息

Hinokuma Nodoka, Sakurai Shunsuke, Shiratori Atsutoshi, Nagahara Keiko, Abe Yoshifusa, Shimizu Takeshi, Fujii Takanari, Mizuno Katsumi, Tomita Hideshi

机构信息

Department of Pediatrics, Showa University School of Medicine, Tokyo, Japan.

Children's Medical Center, Showa University Koto Toyosu Hospital, Tokyo, Japan.

出版信息

SAGE Open Med Case Rep. 2020 Nov 25;8:2050313X20969559. doi: 10.1177/2050313X20969559. eCollection 2020.

DOI:10.1177/2050313X20969559
PMID:33294189
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7705808/
Abstract

Hyponatremic hypertensive syndrome is characterized by hypertension, hyponatremia, and hypokalemia due to unilateral renal artery stenosis. We herein report a 1-year-old hyponatremic hypertensive syndrome infant without persistent hypertension in the acute phase. On the ninth hospital day, his systolic and diastolic blood pressure increased up to 154-160 and 70-84 mmHg, respectively. Acute gastroenteritis and dehydration might transiently mask his hypertension. By percutaneous transluminal balloon angioplasty for right renal artery, his blood pressure finally normalized without antihypertensive drugs. We reviewed 23 previously reported pediatric patients with hyponatremic hypertensive syndrome under the age of 15 years. Including our patient, there are only three reports on hyponatremic hypertensive syndrome without persistent hypertension in the acute phase. Hyponatremic hypertensive syndrome is curable with proper diagnosis and timely intervention. Therefore, pediatricians should pay attention to the signs and symptoms associated with hyponatremic hypertensive syndrome, even if persistent hypertension was absent in the acute phase.

摘要

低钠血症性高血压综合征的特征是由于单侧肾动脉狭窄导致高血压、低钠血症和低钾血症。我们在此报告一名1岁的低钠血症性高血压综合征婴儿,急性期无持续性高血压。在住院第9天,他的收缩压和舒张压分别升至154 - 160 mmHg和70 - 84 mmHg。急性肠胃炎和脱水可能暂时掩盖了他的高血压。通过经皮腔内球囊血管成形术治疗右肾动脉,他的血压最终在未使用降压药物的情况下恢复正常。我们回顾了23例先前报道的15岁以下低钠血症性高血压综合征儿科患者。包括我们的患者在内,仅有3篇关于急性期无持续性高血压的低钠血症性高血压综合征的报道。低钠血症性高血压综合征通过正确诊断和及时干预是可治愈的。因此,儿科医生应注意与低钠血症性高血压综合征相关的体征和症状,即使急性期无持续性高血压。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a7/7705808/4e70bc8bbdf4/10.1177_2050313X20969559-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a7/7705808/17c6e686e445/10.1177_2050313X20969559-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a7/7705808/4e70bc8bbdf4/10.1177_2050313X20969559-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a7/7705808/17c6e686e445/10.1177_2050313X20969559-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a7/7705808/4e70bc8bbdf4/10.1177_2050313X20969559-fig2.jpg

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本文引用的文献

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Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents.临床实践指南:儿童和青少年高血压的筛查和管理。
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Hyponatremic hypertensive syndrome - a retrospective cohort study.低钠血症性高血压综合征——一项回顾性队列研究。
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Hyponatremic-hypertensive syndrome: think of unilateral renal artery stenosis.低钠血症-高血压综合征:想到单侧肾动脉狭窄。
Indian J Pediatr. 2013 Oct;80(10):872-4. doi: 10.1007/s12098-012-0908-4. Epub 2012 Nov 15.
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Hyponatremic hypertensive syndrome in pediatric patients: is it really so rare?儿童低钠性高血压综合征:真的如此罕见吗?
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The hyponatremic hypertensive syndrome in a preterm infant: a case of severe hyponatremia with neurological sequels.一名早产儿的低钠血症性高血压综合征:一例伴有神经后遗症的严重低钠血症病例。
Int J Nephrol. 2011;2011:406515. doi: 10.4061/2011/406515. Epub 2011 Aug 15.
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