Seracini Daniela, Pela Ivana, Favilli Silvia, Bini Roberta M
Paediatric Nephrology, Meyer Hospital, Via Luca Giordano 13, Florence, 50135, Italy.
Pediatr Nephrol. 2006 Jul;21(7):1027-30. doi: 10.1007/s00467-006-0121-7. Epub 2006 May 18.
In this report we present the case of a 15-month-old girl with hyponatraemic-hypertensive syndrome (HHS) caused by stenosis of the left renal artery. On sonographic examination the contralateral non-stenotic kidney appeared enlarged and with cortical hyperechogenicity mimicking a parenchymal lesion. After successful percutaneous transluminal angioplasty, when the girl became normotensive, her serum electrolyte and acid-base balance became normal within a few days. The contralateral non-stenotic kidney hyperechogenicity also disappeared, but only after a period of 6 months, suggesting parenchymal damage due to tubulointerstitial injury, even though reversible. Our case confirms that renovascular hypertension may rarely also be present with HHS in children and that metabolic and morphological alterations are reversible after the resolution of arterial stenosis.
在本报告中,我们介绍了一名15个月大女童的病例,其患有由左肾动脉狭窄引起的低钠血症-高血压综合征(HHS)。超声检查显示,对侧无狭窄的肾脏肿大,皮质回声增强,类似实质性病变。经皮腔内血管成形术成功后,女童血压恢复正常,血清电解质和酸碱平衡在数天内恢复正常。对侧无狭窄肾脏的回声增强也消失了,但这一过程持续了6个月,提示存在因肾小管间质损伤导致的实质性损害,尽管这种损害是可逆的。我们的病例证实,儿童肾血管性高血压很少也会伴有HHS,并且动脉狭窄解除后,代谢和形态学改变是可逆的。