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睾丸癌的多模态影像学图谱综述:从初始分期到再分期

Multimodality Radiological Pictorial Review of Testicular Carcinoma: From Initial Staging to Restaging.

作者信息

Revels Jonathan W, Wang Sherry S, Gangadhar Kiran, Ali Arafat, Ali Al-Amin, Lee Jean H

机构信息

Department of Radiology, University of New Mexico, Albuquerque, NM, USA.

Department of Radiology and Imaging Sciences, University of Utah, Salt Lake, UT, USA.

出版信息

Res Rep Urol. 2020 Dec 1;12:599-613. doi: 10.2147/RRU.S257243. eCollection 2020.

Abstract

With an overall 5-year survival rate >95%, patients with testicular cancer have a great prognosis. Although initial diagnosis is based on clinical examination, imaging does play a significant role in the diagnosis and prognosis of testicular cancer, which are dependent on tumor burden and staging. Successful treatment requires appropriate disease assessment throughout a patient's treatment: evaluating treatment response, restaging, and monitoring for disease recurrence after treatment completion. Ultrasound is usually the initial screening modality for painless testicular masses, and computedtomography (CT) the most commonly used for staging and restaging. However, with regard to seminomas, positron-emission tomography (PET) combined with CT is slowly taking priority. With regard to nonseminomatous germ-cell tumors, PET-CT has not proven to be completely effective, due to a high number of false-negative results. The purpose of this paper is to provide radiologists with a pictorial review of testicular carcinoma from initial staging through posttreatment follow-up.

摘要

睾丸癌患者的总体 5 年生存率>95%,预后良好。虽然初始诊断基于临床检查,但影像学在睾丸癌的诊断和预后中确实起着重要作用,这取决于肿瘤负荷和分期。成功的治疗需要在患者整个治疗过程中进行适当的疾病评估:评估治疗反应、重新分期以及在治疗完成后监测疾病复发。超声通常是无痛性睾丸肿块的初始筛查方式,而计算机断层扫描(CT)是最常用于分期和重新分期的方法。然而,对于精原细胞瘤,正电子发射断层扫描(PET)联合 CT 正逐渐占据优先地位。对于非精原细胞性生殖细胞肿瘤,由于大量假阴性结果,PET-CT 尚未被证明完全有效。本文的目的是为放射科医生提供一份从初始分期到治疗后随访的睾丸癌影像学综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80e0/7718994/4290cc8bcacc/RRU-12-599-g0001.jpg

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