Fontana M H, Coutinho M F, Camargo E dos S, Soviero B, Lima S S, Matusiak R, Dias C G
Hospital da Criança Santo Antonio (HCSA), Porto Alegre.
Arq Neuropsiquiatr. 1987 Dec;45(4):403-11. doi: 10.1590/s0004-282x1987000400007.
The authors report three cases of central nervous system cryptococcosis in children in the first decade of life, from Rio Grande do Sul State, Brazil. Diagnosis was supported by demonstration of Cryptococcus neoformans with India-ink preparations of the spinal fluid and Sabouraud's media culture. Clinical presentation included acute, subacute and chronic forms. Increased intracranial pressure and hydrocephalus were the complications during the course of the disease, and a ventriculoperitoneal shunt was used in one case. Undernutrition was associated with all cases and tubercle bacillus infection with one. Specific therapy was administered to the three patients. One patient was cured and the other two died.
作者报告了巴西南里奥格兰德州10岁以下儿童的3例中枢神经系统隐球菌病病例。脑脊液印度墨汁涂片及沙氏培养基培养发现新型隐球菌，从而支持了诊断。临床表现包括急性、亚急性和慢性形式。颅内压升高和脑积水是疾病过程中的并发症，1例患者使用了脑室腹腔分流术。所有病例均伴有营养不良，1例伴有结核杆菌感染。对3例患者均给予了特异性治疗。1例患者治愈，另外2例死亡。
