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在 COVID 大流行背景下直肠癌的放射治疗管理。

Radiotherapy management of rectal cancer in the backdrop of the COVID pandemic.

机构信息

Department of Radiotherapy and Oncology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.

Department of Radiation Oncology, Kokilaben Dhirubhai Ambani Hospital, Mumbai, India.

出版信息

Cancer Rep (Hoboken). 2021 Apr;4(2):e1320. doi: 10.1002/cnr2.1320. Epub 2020 Dec 9.

DOI:10.1002/cnr2.1320
PMID:33295140
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7883038/
Abstract

BACKGROUND

COVID-19 outbreak was declared as a pandemic by the World Health Organization in March 2020. Over the last 3 months, the pandemic has challenged the diagnosis and treatment of all cancer, including rectal cancer. Constraints in resources call for a change in the treatment strategy without compromising efficacy.

RECENT FINDINGS

Delivery of shorter treatment schedules for radiotherapy offers advantages like short overall treatment time, improved throughput on the machine, improved compliance and reduced risk of transmission of COVID 19. Other strategies include delaying surgery, reducing the intensity of chemotherapy and adoption of organ preservation approach.

CONCLUSION

The curative treatment of rectal cancer should not be hindered during the COVID pandemic, and modifications in the multi-modality treatment will help achieve quality care.

摘要

背景

2020 年 3 月,世界卫生组织宣布 COVID-19 疫情为大流行。在过去的 3 个月中,这场大流行给包括直肠癌在内的所有癌症的诊断和治疗带来了挑战。资源的限制要求改变治疗策略,而不影响疗效。

最近的发现

缩短放疗治疗方案的时间提供了许多优势,如缩短总治疗时间、提高机器的吞吐量、提高患者的顺应性和降低 COVID-19 传播的风险。其他策略包括延迟手术、减少化疗的强度和采用器官保存方法。

结论

在 COVID 大流行期间,不应阻碍直肠癌的治愈性治疗,多模式治疗的改变将有助于实现高质量的护理。

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本文引用的文献

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Prostate Cancer Radiation Therapy Recommendations in Response to COVID-19.应对新型冠状病毒肺炎的前列腺癌放射治疗建议
Adv Radiat Oncol. 2020 Oct 29;5(Suppl 1):26-32. doi: 10.1016/j.adro.2020.10.003. eCollection 2020 Nov.
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Treatment delays in oncology patients during COVID-19 pandemic: A perspective.COVID-19大流行期间肿瘤患者的治疗延迟:一种观点。
J Glob Health. 2020 Jun;10(1):010367. doi: 10.7189/jogh.10.010367.
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Lockdown poses new challenges for cancer care in India.封锁给印度的癌症护理带来了新挑战。
Lancet Oncol. 2020 Jul;21(7):884. doi: 10.1016/S1470-2045(20)30312-0. Epub 2020 May 29.
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Caring for Patients with Rectal Cancer During the COVID-19 Pandemic.在 COVID-19 大流行期间照顾直肠癌患者。
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Caring for patients with cancer in the COVID-19 era.在 COVID-19 时代照顾癌症患者。
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Recommendations for the use of radiation therapy in managing patients with gastrointestinal malignancies in the era of COVID-19.在 COVID-19 时代管理胃肠道恶性肿瘤患者中放射治疗的应用建议。
Radiother Oncol. 2020 Jul;148:194-200. doi: 10.1016/j.radonc.2020.04.010. Epub 2020 Apr 13.
7
International expert consensus statement regarding radiotherapy treatment options for rectal cancer during the COVID 19 pandemic.关于2019年冠状病毒病大流行期间直肠癌放射治疗选择的国际专家共识声明。
Radiother Oncol. 2020 Jul;148:213-215. doi: 10.1016/j.radonc.2020.03.039. Epub 2020 Apr 2.
8
Management of Locally Advanced Rectal Cancer During The COVID-19 Pandemic: A Necessary Paradigm Change at Memorial Sloan Kettering Cancer Center.新冠疫情期间局部晚期直肠癌的管理:纪念斯隆凯特琳癌症中心必要的范式转变
Adv Radiat Oncol. 2020 Apr 22;5(4):687-689. doi: 10.1016/j.adro.2020.04.011. eCollection 2020 Jul-Aug.
9
Provision of cancer care during the COVID-19 pandemic.在 COVID-19 大流行期间提供癌症护理。
Nat Rev Clin Oncol. 2020 Jun;17(6):329-331. doi: 10.1038/s41571-020-0370-6.
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Urgent dental care for patients during the COVID-19 pandemic.新冠疫情期间为患者提供紧急牙科护理。
Lancet. 2020 Apr 18;395(10232):1257. doi: 10.1016/S0140-6736(20)30806-0. Epub 2020 Apr 3.