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局部应用1.5%阿奇霉素滴眼液有效治疗儿童眼部酒渣鼻

[Pediatric ocular rosacea effectively treated with topical 1.5% azithromycin eye drops].

作者信息

Starosta Daniela A, Lorenz Birgit

机构信息

Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Gießen und Marburg GmbH, Standort Gießen, Justus-Liebig-Universität Gießen, Friedrichstr. 18, 35392, Gießen, Deutschland.

出版信息

Ophthalmologe. 2021 Jan;118(1):68-73. doi: 10.1007/s00347-020-01279-z.

DOI:10.1007/s00347-020-01279-z
PMID:33296015
Abstract

Ocular rosacea in children is a rare but often underdiagnosed condition. It is typically associated with chronic blepharoconjunctivitis, chalazia, corneal opacity and corneal neovascularization. The recommended treatment consists of topical (eyelid hygiene, steroids, cyclosporin, lubricants) and systemic (antibiotics e.g. erythromycin) measures. This case series of 8 children demonstrates the efficacy of local 1.5% azithromycin treatment together with eyelid hygiene in pediatric ocular rosacea. A further advantage of this topical treatment is that the required application of only twice daily for 3 days followed by 7 days without treatment is convenient and improves adherence to treatment.

摘要

儿童眼部酒渣鼻是一种罕见但常被漏诊的病症。它通常与慢性睑结膜炎、睑板腺囊肿、角膜混浊和角膜新生血管形成有关。推荐的治疗方法包括局部(眼睑清洁、类固醇、环孢素、润滑剂)和全身(抗生素,如红霉素)措施。这个包含8名儿童的病例系列证明了局部使用1.5%阿奇霉素联合眼睑清洁在儿童眼部酒渣鼻治疗中的疗效。这种局部治疗的另一个优点是,只需每天应用两次,持续3天,然后7天不治疗,既方便又能提高治疗依从性。

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[Pediatric ocular rosacea effectively treated with topical 1.5% azithromycin eye drops].局部应用1.5%阿奇霉素滴眼液有效治疗儿童眼部酒渣鼻
Ophthalmologe. 2021 Jan;118(1):68-73. doi: 10.1007/s00347-020-01279-z.
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J Dtsch Dermatol Ges. 2025 Jun;23(6):684-691. doi: 10.1111/ddg.15693. Epub 2025 Mar 22.
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Ocular Rosacea: An Updated Review.眼部酒渣鼻:最新综述
Cornea. 2025 Apr 1;44(4):525-537. doi: 10.1097/ICO.0000000000003785. Epub 2025 Jan 14.

本文引用的文献

1
Pediatric ocular acne rosacea: long-term treatment with systemic antibiotics.儿童眼部酒渣鼻:全身性抗生素的长期治疗
Am J Ophthalmol. 2006 Nov;142(5):816-21. doi: 10.1016/j.ajo.2006.06.047.