School of Medicine, Wayne State University, Detroit, USA.
Department of Dermatology, Wayne State University, Detroit, USA.
Int J Dermatol. 2021 Oct;60(10):1199-1210. doi: 10.1111/ijd.15344. Epub 2020 Dec 9.
Hair supplements are a vast and growing industry. Patients often turn to oral supplements to address hair concerns as they are easily accessible. There are numerous products on the market, many with thousands of reviews (both positive and negative). Nutritional supplements are regulated by the FDA as foods instead of drugs, meaning they do not have to prove their efficacy and safety before becoming available to consumers. While some oral supplements have strong evidence supporting their use for hair growth, many ingredients have not been tested in clinical trials, have only in vitro evidence for hair growth, or have only been tested in animals. Given these industry characteristics, it is important for dermatologists to be aware of the safety and utility of these ingredients to provide appropriate counseling to their patients. The goal of this review is to evaluate the efficacy of popular hair growth oral supplement ingredients and formulations. This review does not address the topical formulations of these ingredients and their effects on hair growth.
毛发补充剂是一个庞大且不断增长的行业。由于口服补充剂易于获取，患者通常会选择它们来解决毛发问题。市场上有许多产品，其中许多都有数千条（正面和负面的）评论。营养补充剂受 FDA 监管为食品而不是药物，这意味着在向消费者提供之前，它们不必证明其疗效和安全性。虽然一些口服补充剂有强有力的证据支持其用于毛发生长，但许多成分尚未经过临床试验测试，仅在体外有毛发生长证据，或仅在动物身上进行了测试。鉴于这些行业特点，皮肤科医生了解这些成分的安全性和实用性非常重要，以便为患者提供适当的咨询。本综述的目的是评估流行的毛发生长口服补充剂成分和配方的疗效。本综述不涉及这些成分的局部制剂及其对毛发生长的影响。
