Iyengar Laxmi, Li Jane
Skin Health Institute, Melbourne.
Endeavour Hills Medical Centre, Melbourne.
Aust Prescr. 2025 Jun;48(3):93-97. doi: 10.18773/austprescr.2025.020.
Androgenetic alopecia, commonly referred to as male or female pattern hair loss, is a prevalent condition encountered in clinical practice. It is important to identify potential underlying causes and differentiate it from other forms of hair loss, which may require referral to a dermatologist for management. Pharmacological treatments for female pattern hair loss include minoxidil (topical and oral) and antiandrogens such as spironolactone. For male pattern hair loss, minoxidil and 5-alpha-reductase inhibitors (e.g. finasteride, dutasteride) can be used. Combination therapy is commonly employed, with clinical improvement typically requiring a minimum of 6 months. Supplements and other treatments have varying levels of evidence, and counselling is important to help patients make informed decisions about their management.
雄激素性脱发,通常称为男性或女性型脱发,是临床实践中常见的一种病症。识别潜在的根本原因并将其与其他形式的脱发区分开来很重要,这可能需要转诊给皮肤科医生进行治疗。女性型脱发的药物治疗包括米诺地尔(局部和口服)以及抗雄激素药物,如螺内酯。对于男性型脱发,可使用米诺地尔和5α-还原酶抑制剂(如非那雄胺、度他雄胺)。通常采用联合治疗,临床改善通常至少需要6个月。补充剂和其他治疗方法的证据水平各不相同,提供咨询对于帮助患者就其治疗做出明智的决定很重要。