Potential of AT-R-Biased Agonists in Pediatric Heart Failure.
作者信息
Port J David
机构信息
Department of Medicine, Division of Cardiology, and Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Denver, Colorado, USA.
出版信息
JACC Basic Transl Sci. 2020 Nov 23;5(11):1070-1072. doi: 10.1016/j.jacbts.2020.09.008. eCollection 2020 Nov.
Abstract
摘要
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本文引用的文献
1
β-Arrestin-Biased AT Agonist TRV027 Causes a Neonatal-Specific Sustained Positive Inotropic Effect Without Increasing Heart Rate.β-抑制蛋白偏向性血管紧张素 II 激动剂TRV027可产生新生儿特异性的持续正性肌力作用而不增加心率。
JACC Basic Transl Sci. 2020 Nov 11;5(11):1057-1069. doi: 10.1016/j.jacbts.2020.08.011. eCollection 2020 Nov.
2
Update on pediatric heart failure.儿科心力衰竭的最新进展。
Curr Opin Pediatr. 2019 Oct;31(5):598-603. doi: 10.1097/MOP.0000000000000807.
3
Differential Response to Heart Failure Medications in Children.儿童对心力衰竭药物的不同反应。
Prog Pediatr Cardiol. 2018 Jun;49:27-30. doi: 10.1016/j.ppedcard.2018.01.011.
4
Design for the sacubitril/valsartan (LCZ696) compared with enalapril study of pediatric patients with heart failure due to systemic left ventricle systolic dysfunction (PANORAMA-HF study).沙库巴曲缬沙坦（LCZ696）与依那普利治疗因左心室收缩功能障碍导致心力衰竭的儿科患者的比较研究（全景-心力衰竭研究）。
Am Heart J. 2017 Nov;193:23-34. doi: 10.1016/j.ahj.2017.07.006. Epub 2017 Jul 17.
5
Pediatric dilated cardiomyopathy hearts display a unique gene expression profile.小儿扩张型心肌病心脏表现出独特的基因表达谱。
JCI Insight. 2017 Jul 20;2(14). doi: 10.1172/jci.insight.94249.
6
Biased ligand of the angiotensin II type 1 receptor in patients with acute heart failure: a randomized, double-blind, placebo-controlled, phase IIB, dose ranging trial (BLAST-AHF).血管紧张素 II 型 1 受体偏倚配体在急性心力衰竭患者中的应用：一项随机、双盲、安慰剂对照、IIB 期、剂量范围试验（BLAST-AHF）。
Eur Heart J. 2017 Aug 7;38(30):2364-2373. doi: 10.1093/eurheartj/ehx196.
7
Angiotensin II activates Ca 1.2 Ca channels through β-arrestin2 and casein kinase 2 in mouse immature cardiomyocytes.血管紧张素II通过β-抑制蛋白2和酪蛋白激酶2激活小鼠未成熟心肌细胞中的Ca 1.2钙通道。
J Physiol. 2017 Jul 1;595(13):4207-4225. doi: 10.1113/JP273883. Epub 2017 Apr 20.
8
Carvedilol for children and adolescents with heart failure: a randomized controlled trial.卡维地洛用于儿童和青少年心力衰竭患者：一项随机对照试验。
JAMA. 2007 Sep 12;298(10):1171-9. doi: 10.1001/jama.298.10.1171.
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