Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Halle (Saale), Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Cochlear Implants Int. 2021 May;22(3):121-127. doi: 10.1080/14670100.2020.1850032. Epub 2020 Dec 9.
To measure the effect of burst duration, stimulated electrode position, and stimulation level on the P1-N1-P2 electrically evoked cortical auditory potentials (eCAEPs) elicited via the direct stimulation of selected electrode contacts on a cochlear implant (CI) electrode array. Prospective observational study of 20 adult cochlear implant users with a MED-EL CI system. eCAEPs were recorded simultaneously with the (Interacoustics) and the (Nihon Kohden) recording systems. Tone bursts with durations of 50, 100, and 150 ms were used for stimulation at the maximum comfortable loudness level (MCL) and MCL minus 50% dynamic range (DR) at selected apical, medial, and basal intracochlear electrodes. Individual P1-N1 and N1-P2 amplitudes were significantly higher at the MCL level of stimulation than at the MCL minus 50% DR. Burst length and stimulated electrode position did not affect the eCAEP responses. Residual noise was lower in the system. This study shows the feasibility of eCAEP recording using the MAESTRO software. The eCAEP morphology was independent of the burst duration and the stimulated electrode position. This allows a large flexibility in using direct cochlear stimulation to elicit eCAEPs.
为了测量短声时长、刺激电极位置和刺激水平对通过对植入式人工耳蜗（CI）电极阵列的选定电极触点的直接刺激产生的 P1-N1-P2 电诱发皮质听觉诱发电位（eCAEPs）的影响。这是一项对 20 名成年植入式人工耳蜗使用者的前瞻性观察研究，他们使用的是 MED-EL CI 系统。eCAEPs 同时使用 （Interacoustics） 和 （Nihon Kohden） 记录系统进行记录。使用时长为 50、100 和 150 ms 的短声在最大舒适响度级（MCL）和选定的耳蜗内顶、中、底电极的 MCL 减 50%动态范围（DR）下进行刺激。在刺激的 MCL 水平下，个体的 P1-N1 和 N1-P2 振幅明显高于 MCL 减 50% DR。短声长度和刺激电极位置对 eCAEP 反应没有影响。 系统中的残余噪声较低。这项研究表明使用 MAESTRO 软件进行 eCAEP 记录是可行的。eCAEP 形态与短声时长和刺激电极位置无关。这允许在使用直接耳蜗刺激产生 eCAEPs 时具有很大的灵活性。
