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土耳其南部烧伤住院患者的描述性流行病学及转归:特定年龄的死亡率模式

The Descriptive Epidemiology and Outcomes of Hospitalized Burn Patients in Southern Turkey: Age-Specific Mortality Patterns.

作者信息

Gurbuz Kayhan, Demir Mete

机构信息

Burn Center, Department of General Surgery, Adana City Training and Research Hospital, Turkey.

出版信息

J Burn Care Res. 2021 Aug 4;42(4):743-751. doi: 10.1093/jbcr/iraa206.

Abstract

The current descriptive analysis was designed to document the common epidemiologic characteristics and outcomes of burn injuries, and age-specific mortality patterns covering all age groups admitted for treatment to the Burn Center of Adana City Training and Research Hospital. Medical records were retrospectively analyzed. The patients were stratified into two age groups as pediatric and adults, and then into 10 sub-age groups. Among the 946 patients of the study population, there were 24 mortalities with a mortality rate of 2.5%. Patients within the age range of 70 to 79 years had the highest mortality rate of 33.3%; followed by 60 to 69, 80+, 18 to 29, 10 to 17, and <5 sub-age groups, whose mortality rates were 13.0%, 7.8%, 7.2%, 2.4%, and 0.5%, respectively. In terms of multivariate regression analysis of factors predicting mortality among burn patients in all age groups, fire-flame related burns, age ≥18 years, TBSA burned ≥20% (TBSA ≥20%), the existence of inhalation injury, deep partially/full-thickness burns were found to be significant prognostic factors of mortality. The strongest association was seen in TBSA ≥60% segment (P < .0001), which had 25.9 times more death risk. As expected, a similar trend was detected when the age groups stratified into age groups, and the strongest association was in the 60+ sub-age group (P < .0001), whose had 5.84 times more likely death; followed by 29 to 59 and 18 to 29 sub-age groups, with the odds ratios of 2.12 (95% confidence interval = 1.25-3.61) and 2.08 (95% confidence interval = 1.90-4.05), respectively. Oppose to these findings; the 0 to 17 sub-age group was not found to have a statistically significant effect in predicting mortality.

摘要

本次描述性分析旨在记录烧伤的常见流行病学特征及转归,以及阿达纳市培训与研究医院烧伤中心收治的所有年龄段患者的特定年龄死亡率模式。对病历进行了回顾性分析。将患者分为儿童和成人两个年龄组,然后再细分为10个亚年龄组。在946例研究人群患者中,有24例死亡,死亡率为2.5%。70至79岁年龄组的死亡率最高,为33.3%;其次是60至69岁、80岁及以上、18至29岁、10至17岁和5岁以下亚年龄组,其死亡率分别为13.0%、7.8%、7.2%、2.4%和0.5%。在对所有年龄组烧伤患者死亡率预测因素的多因素回归分析中,发现火焰相关烧伤、年龄≥18岁、烧伤总面积≥20%(TBSA≥20%)、存在吸入性损伤、深度部分/全层烧伤是死亡率的重要预后因素。在烧伤总面积≥60%组关联最强(P<.0001),其死亡风险高25.9倍。正如预期的那样,按年龄分层后各年龄组也发现了类似趋势,关联最强的是60岁及以上亚年龄组(P<.0001),其死亡可能性高5.84倍;其次是29至59岁和18至29岁亚年龄组,优势比分别为2.12(95%置信区间=1.25 - 3.61)和2.08(95%置信区间=1.90 - 4.05)。与这些结果相反,0至17岁亚年龄组在预测死亡率方面未发现有统计学意义的影响。

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