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加拿大马尼托巴省的 HIV 关怀链:满足当地需求的方法、措施和估计。

The HIV care cascade in Manitoba, Canada: Methods, measures, and estimates to meet local needs.

机构信息

Institute for Global Public Health, Rady Faculty of Health Science, University of Manitoba, R065 Medical Rehabilitation Building - 771 McDermot Ave. Winnipeg, Manitoba R3E 0T6 Canada.

Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences University of Manitoba Health Sciences Centre - 820 Sherbrook St. Winnipeg, Manitoba R3A 1R9 Canada.

出版信息

J Clin Epidemiol. 2021 Apr;132:26-33. doi: 10.1016/j.jclinepi.2020.11.026. Epub 2020 Dec 8.

Abstract

BACKGROUND AND OBJECTIVE

We describe the development of the first HIV care cascade for Manitoba, Canada, detailing steps taken to establish indicator definitions for each cascade step, and derive a full complement of local estimates.

METHODS

Manitoba is a Canadian Prairie Province with disproportionately high annual HIV incidence. In 2013, a clinical cohort of people living with HIV was established within the primary HIV care program in Manitoba. Using cohort data from 2017, we describe the creation of a set of indicator definitions and calculate estimates for each cascade step to create the first Manitoban cascade model.

RESULTS

Of the 703 cohort participants categorized as alive and diagnosed, 638 (90.8%) were in care, 606 (86.2%) retained in care, 573 (81.5%) on treatment, and 523 (74.4%) virologically suppressed. The greatest point of leakage occurred between the first and second steps; 9.3% of those alive and diagnosed in 2017 were not in care in the same calendar year.

CONCLUSION

This is the first comprehensive examination of HIV clinical epidemiology in Manitoba using a cascade framework, with the potential inform programming to improve service coverage within Manitoba and significantly contribute to evidence informing provincial policies to support these efforts.

摘要

背景与目的

我们描述了加拿大马尼托巴省的第一个 HIV 关怀链的开发过程,详细介绍了为每个关怀链步骤建立指标定义的步骤,并得出了完整的本地估计值。

方法

马尼托巴省是加拿大草原省份,HIV 年发病率过高。2013 年,在马尼托巴省的主要 HIV 护理计划中建立了一个艾滋病毒感染者临床队列。利用 2017 年的队列数据,我们描述了一套指标定义的创建,并计算了每个关怀链步骤的估计值,以创建第一个马尼托巴关怀链模型。

结果

在被归类为存活和诊断的 703 名队列参与者中,638 名(90.8%)在接受治疗,606 名(86.2%)在接受治疗,573 名(81.5%)在接受治疗,523 名(74.4%)病毒载量得到抑制。最大的泄漏点发生在第一和第二步之间;2017 年存活和诊断的人中,有 9.3%的人当年没有在接受治疗。

结论

这是首次使用关怀链框架全面检查马尼托巴省的 HIV 临床流行病学,有可能为改善马尼托巴省的服务覆盖范围提供信息,并为支持这些努力的省级政策提供重要的证据。

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