Nicolau Ioana A, Shokoohi Mostafa, McBane Joanne E, Pogany Lisa, Popovic Nashira, Nicholson Valerie, Hillier Sean, Aran Niloufar, Brophy Jason, Burt Kimberley, Cox Joseph, de Pokomandy Alexandra, Kakkar Fatima, Kelly Deborah, Kerkerian Geneviève, Kogilwaimath Siddharth, Kroch Abigail, Dias Lima Viviane, Linthwaite Blake, Mbuagbaw Lawrence, McClarty Leigh, Turvey Shannon, Owino Maureen, Martin Carrie, Hogg Robert S, Loutfy Mona
Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Women's College Research Institute, Women's College Hospital, Toronto, Ontario, Canada.
J Assoc Med Microbiol Infect Dis Can. 2022 Sep 27;7(3):247-268. doi: 10.3138/jammi-2022-0007. eCollection 2022 Sep.
The HIV care cascade is an indicators-framework used to assess achievement of HIV clinical targets including HIV diagnosis, HIV care initiation and retention, initiation of antiretroviral therapy, and attainment of viral suppression for people living with HIV.
The HIV Care Cascade Research Development Team at the CIHR Canadian HIV Trials Network Clinical Care and Management Core hosted a two-day virtual workshop to present HIV care cascade data collected nationally from local and provincial clinical settings and national cohort studies. The article summarizes the workshop presentations including the indicators used and available findings and presents the discussed challenges and recommendations.
Identified challenges included (1) inconsistent HIV care cascade indicator definitions, (2) variability between the use of nested UNAIDS's targets and HIV care cascade indicators, (3) variable analytic approaches based on differing data sources, (4) reporting difficulties in some regions due to a lack of integration across data platforms, (5) lack of robust data on the first stage of the care cascade at the sub-national level, and (6) inability to integrate key socio-demographic data to estimate population-specific care cascade shortfalls.
There were four recommendations: standardization of HIV care cascade indicators and analyses, additional funding for HIV care cascade data collection, database maintenance and analyses at all levels, qualitative interviews and case studies characterizing the stories behind the care cascade findings, and employing targeted positive-action programs to increase engagement of key populations in each HIV care cascade stage.
艾滋病病毒(HIV)关怀流程是一个指标框架,用于评估HIV临床目标的达成情况,这些目标包括HIV诊断、开始并持续接受HIV治疗、启动抗逆转录病毒治疗以及实现HIV感染者的病毒抑制。
加拿大卫生研究院(CIHR)加拿大HIV试验网络临床护理与管理核心的HIV关怀流程研究开发团队举办了一场为期两天的虚拟研讨会,以展示从地方和省级临床机构以及全国队列研究中收集到的全国性HIV关怀流程数据。本文总结了研讨会上的报告内容,包括所使用的指标和现有研究结果,并介绍了所讨论的挑战和建议。
确定的挑战包括:(1)HIV关怀流程指标定义不一致;(2)联合国艾滋病规划署(UNAIDS)嵌套目标的使用与HIV关怀流程指标之间存在差异;(3)基于不同数据源的分析方法各异;(4)由于数据平台缺乏整合,一些地区存在报告困难;(5)国家以下层面缺乏关于关怀流程第一阶段的可靠数据;(6)无法整合关键社会人口数据以估计特定人群的关怀流程缺口。
提出了四项建议:HIV关怀流程指标和分析的标准化;为HIV关怀流程数据收集、各级数据库维护和分析提供额外资金;进行定性访谈和案例研究,以描述关怀流程结果背后的情况;以及采用有针对性的积极行动计划,以提高关键人群在HIV关怀流程各阶段的参与度。