Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
International Clinical Research Center, St. Anne's University Hospital, Brno, Czechia.
Cerebrovasc Dis. 2021;50(1):54-61. doi: 10.1159/000512180. Epub 2020 Dec 10.
There are few contemporary epidemiological data on stroke for Central Europe. We performed a population-based study evaluating the incidence of stroke, stroke types, and ischemic stroke (IS) subtypes in Brno, the second biggest city in the Czech Republic (CR).
Using the National Registry of Hospitalized Patients, and hospital databases, we identified all patients hospitalized with a stroke diagnosis in Brno hospitals in 2011. For Brno residents with validated stroke diagnosis, we calculated (a) the overall incidence of hospitalized stroke, (b) incidence rates for IS, subarachnoid hemorrhage (SAH) and intracerebral hemorrhage (ICH), and (c) incidence rates for IS subtypes. We calculated the average annual age- and sex-standardized incidence (European Standard Population and World Health Organization), to compare our results with other studies.
The overall crude incidence of stroke in Brno was 213/100,000 population. The incidence of stroke for stroke types were as follows: SAH, 6.9; ICH, 26.4; and IS, 180 cases per 100,000 population, respectively. The WHO-standardized annual stroke incidence was 107 for all strokes and 88 for IS, 14.4 for ICH, and 5 for SAH. For IS subtypes, the WHO-standardized incidence was large artery atherosclerosis 25.8, cardioembolism 27.8, lacunar 21.6, other determined etiology 6.2, and undetermined etiology 6.5 cases per 100,000 population.
The stroke incidence is lower than that previously reported for the CR and Eastern Europe probably reflecting socioeconomic changes in post-communistic countries in the region. These findings could contribute to stroke prevention strategies and influence health policies.
中欧地区目前仅有少量关于中风的当代流行病学数据。我们进行了一项基于人群的研究，评估捷克共和国第二大城市布尔诺的中风发病率、中风类型和缺血性中风（IS）亚型。
我们使用国家住院患者登记处和医院数据库，确定了 2011 年布尔诺医院所有中风住院患者的病例。对于经过验证的中风诊断的布尔诺居民，我们计算了（a）住院中风的总体发病率，（b）IS、蛛网膜下腔出血（SAH）和脑内出血（ICH）的发病率，以及（c）IS 亚型的发病率。我们计算了平均年年龄和性别标准化发病率（欧洲标准人口和世界卫生组织），以将我们的结果与其他研究进行比较。
布尔诺的中风总粗发病率为 213/100,000 人。中风类型的发病率如下：SAH 为 6.9；ICH 为 26.4；IS 为每 100,000 人 180 例。所有中风和 IS 的世界卫生组织标准化年发病率分别为 107 和 88，ICH 为 14.4，SAH 为 5。对于 IS 亚型，世界卫生组织标准化发病率为大动脉粥样硬化 25.8、心源性栓塞 27.8、腔隙性 21.6、其他确定病因 6.2 和未确定病因 6.5 例/100,000 人。
中风发病率低于捷克共和国和东欧以前的报告，这可能反映了该地区后共产主义国家的社会经济变化。这些发现可能有助于中风预防策略，并影响卫生政策。
