Shahi Shahriar, Farhoudi Mehdi, Dizaj Solmaz Maleki, Sharifi Simin, Sadigh-Eteghad Saeed, Goh Khang Wen, Ming Long Chiau, Dhaliwal Jagjit Singh, Salatin Sara
Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz 5166/15731, Iran.
Neurosciences Research Center (NSRC), Tabriz University of Medical Sciences, Tabriz 5166/15731, Iran.
J Clin Med. 2022 Oct 2;11(19):5854. doi: 10.3390/jcm11195854.
One of the primary causes of disability and mortality in the adult population worldwide is stroke. A person's general health is significantly impacted by their oral and dental health. People who have poor oral health are more susceptible to conditions such as stroke. Stroke risk has long been linked to oral and dental conditions. The risk of stroke and its cost impact on the healthcare systems appear to be significantly reduced as a result of the decline in the incidence and prevalence of oral and dental illnesses. Hypothetically, better management of oral hygiene and dental health lead to reduced stroke risk. To the authors' best knowledge, for the first time, the potential link between dental health and stroke were cross-examined. The most typical stroke symptoms, oral and dental illnesses linked to stroke, and the role of oral healthcare professionals in stroke prevention are revealed. The potential mediating processes and subsequent long-term cognitive and functional neurological outcomes are based on the available literature. It must be noted that periodontal diseases and tooth loss are two common oral health measures. Lack of knowledge on the effects of poor oral health on systemic health together with limited access to primary medical or dental care are considered to be partially responsible for the elevated risk of stroke. Concrete evidence confirming the associations between oral inflammatory conditions and stroke in large cohort prospective studies, stratifying association between oral disease severity and stroke risk and disease effects on stroke survival will be desirable. In terms of clinical pathology, a predictive model of stroke as a function of oral health status, and biomarkers of systemic inflammation could be useful for both cardiologists and dentists.
全球成年人口致残和死亡的主要原因之一是中风。一个人的总体健康会受到其口腔和牙齿健康的显著影响。口腔健康状况不佳的人更容易患中风等疾病。中风风险长期以来一直与口腔和牙齿疾病有关。由于口腔和牙齿疾病的发病率和患病率下降,中风风险及其对医疗系统的成本影响似乎显著降低。从理论上讲,更好地管理口腔卫生和牙齿健康会降低中风风险。据作者所知,首次对牙齿健康与中风之间的潜在联系进行了交叉检验。揭示了最典型的中风症状、与中风相关的口腔和牙齿疾病,以及口腔保健专业人员在中风预防中的作用。基于现有文献探讨了潜在的中介过程以及随后的长期认知和功能性神经学结果。必须指出的是,牙周疾病和牙齿脱落是两种常见的口腔健康指标。对口腔健康不佳对全身健康影响的认识不足,以及获得初级医疗或牙科护理的机会有限,被认为是中风风险升高的部分原因。在大型队列前瞻性研究中,证实口腔炎症性疾病与中风之间的关联、区分口腔疾病严重程度与中风风险之间的关联以及疾病对中风存活的影响的具体证据将是很有必要的。就临床病理学而言,作为口腔健康状况函数的中风预测模型以及全身炎症的生物标志物可能对心脏病专家和牙医都有用。