Weimar Institute, 20601 West Paoli Lane, Weimar, CA 95736, United States.
Weimar Institute, 20601 West Paoli Lane, Weimar, CA 95736, United States.
Med Hypotheses. 2021 Jan;146:110363. doi: 10.1016/j.mehy.2020.110363. Epub 2020 Nov 16.
COVID-19 is a new contagious disease caused by a new coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is a disease that has reached every continent in the world; it has overloaded the medical system worldwide and it has been declared a pandemic by the World Health Organization. Currently there is no definite treatment for COVID-19. We realize that host immunity is a critical factor in the outcome of coronavirus 2 infection. Here, however, we review the pathophysiology of the disease with a focus on searching for what we can do to combat this new disease. From this, we find that coronavirus is sensitive to heat. We have thus focused on this area of vulnerability of the virus. The emphasis of this hypothesis is on the action of body heat-internal (fever) and external (heat treatment)-in activating the immune system and its antiviral activities, and specifically related to the coronavirus. We hypothesize from this review that heat treatments has the potential to prevent COVID-19 and to decrease the severity of mild and moderate cases of Coronavirus. We propose heat treatments for this uncontrolled worldwide coronavirus pandemic while studies are being done to test the effectiveness of heat treatments in the prevention and treatment of COVID-19.
新型冠状病毒病(COVID-19)是由一种新型冠状病毒引起的新发传染病,这种新型冠状病毒被称为严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)。COVID-19 已蔓延至世界各大洲;它使全球医疗系统不堪重负,世界卫生组织已宣布其为大流行。目前,尚无针对 COVID-19 的明确治疗方法。我们意识到宿主免疫力是冠状病毒 2 感染结局的一个关键因素。然而,在这里,我们重点研究了疾病的病理生理学,以寻找对抗这种新发疾病的方法。由此,我们发现冠状病毒对热敏感。因此,我们关注了病毒的这一弱点。该假说的重点是身体热量(发热)和外部热量(热疗)对内激活免疫系统及其抗病毒作用,特别是与冠状病毒相关的作用。我们从这一综述中推测,热疗有可能预防 COVID-19 并降低轻症和中度冠状病毒病例的严重程度。我们建议在进行研究以测试热疗在 COVID-19 预防和治疗中的有效性的同时,对这种不受控制的全球冠状病毒大流行采用热疗。