Weill Cornell School of Medicine, New York, NY, USA.
Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
J Cardiovasc Comput Tomogr. 2021 Mar-Apr;15(2):93-109. doi: 10.1016/j.jcct.2020.11.002. Epub 2020 Nov 9.
Coronary computed tomographic angiography (CCTA) provides a wealth of clinically meaningful information beyond anatomic stenosis alone, including the presence or absence of nonobstructive atherosclerosis and high-risk plaque features as precursors for incident coronary events. There is, however, no uniform agreement on how to identify and quantify these features or their use in evidence-based clinical decision-making. This statement from the Society of Cardiovascular Computed Tomography and North American Society of Cardiovascular Imaging addresses this gap and provides a comprehensive review of the available evidence on imaging of coronary atherosclerosis. In this statement, we provide standardized definitions for high-risk plaque (HRP) features and distill the evidence on the effectiveness of risk stratification into usable practice points. This statement outlines how this information should be communicated to referring physicians and patients by identifying critical elements to include in a structured CCTA report - the presence and severity of atherosclerotic plaque (descriptive statements, CAD-RADS™ categories), the segment involvement score, HRP features (e.g., low attenuation plaque, positive remodeling), and the coronary artery calcium score (when performed). Rigorous documentation of atherosclerosis on CCTA provides a vital opportunity to make recommendations for preventive care and to initiate and guide an effective care strategy for at-risk patients.
冠状动脉计算机断层血管造影术(CCTA)提供了比单纯解剖学狭窄更丰富的临床有意义的信息,包括非阻塞性动脉粥样硬化的存在与否,以及作为冠状动脉事件发生前兆的高危斑块特征。然而,对于如何识别和量化这些特征,以及如何将其用于基于证据的临床决策,目前尚无统一的共识。本心血管计算机断层成像学会和北美心血管成像学会的声明旨在填补这一空白,并对冠状动脉粥样硬化的影像学进行全面综述。在本声明中,我们为高危斑块(HRP)特征提供了标准化的定义,并将风险分层的有效性证据提炼为可用于实践的要点。本声明概述了如何通过确定结构性 CCTA 报告中应包含的关键要素(包括动脉粥样硬化斑块的存在和严重程度(描述性陈述,CAD-RADS™类别)、节段受累评分、HRP 特征(如低衰减斑块、正性重构)和冠状动脉钙化评分(如进行)),将这些信息传达给转诊医生和患者。在 CCTA 上对动脉粥样硬化进行严格的记录,为提供预防性保健建议、为高危患者启动和指导有效的护理策略提供了重要机会。