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肺癌患者的营养支持:现状。

Nutritional Support in Lung Cancer Patients: The State of the Art.

机构信息

UOSD di Nutrizione Avanzata in Oncologia, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.

UOC di Nutrizione Clinica, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.

出版信息

Clin Lung Cancer. 2021 Jul;22(4):e584-e594. doi: 10.1016/j.cllc.2020.10.008. Epub 2020 Oct 21.

Abstract

Lung cancer (LC) represents the most commonly diagnosed neoplasm worldwide for both sexes and is the leading cause of cancer mortality. Malnutrition is a comorbidity frequently found in neoplastic patients, but it remains often underestimated and thus undertreated. In this review, we aimed to investigate the incidence of malnutrition among LC patients according to different screening and assessment tools, to evaluate the impact of weight loss and body composition on survival, and to analyze the efficacy of different nutritional interventions in this setting. Although malnutrition, weight loss, and body composition changes can affect survival and other clinical outcomes in LC patients, the role of nutritional interventions is not yet strongly proven, and further studies are recommended. Nevertheless, screening, assessing, and eventually treating malnutrition in LC patients are strongly recommended, according to the most recent nutritional intervention guidelines for oncology patients.

摘要

肺癌(LC)是全球男女最常见的肿瘤诊断,也是癌症死亡的主要原因。营养不良是肿瘤患者常见的合并症,但往往被低估和治疗不足。在这篇综述中,我们旨在根据不同的筛查和评估工具调查 LC 患者营养不良的发生率,评估体重减轻和身体成分对生存的影响,并分析这一人群中不同营养干预措施的疗效。尽管营养不良、体重减轻和身体成分变化会影响 LC 患者的生存和其他临床结局,但营养干预的作用尚未得到充分证实,因此需要进一步研究。然而,根据最新的肿瘤患者营养干预指南,强烈建议筛查、评估和治疗 LC 患者的营养不良。

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