Li Jianjun, Zheng Jing
Department of Cardiothoracic Surgery, Banan Hospital Affiliated to Chongqing Medical University, Chongqing 401320, P.R. China.
Department of Operations Management, Banan Hospital Affiliated to Chongqing Medical University, Chongqing 401320, P.R. China.
Oncol Lett. 2024 Jan 23;27(3):118. doi: 10.3892/ol.2024.14251. eCollection 2024 Mar.
Thoracoscopic lobectomy is the main type of surgical treatment for lung cancer. Postoperative patients have complications and decreased pulmonary function, which affects their discharge time and quality of life. Lung ventilator training has been shown to promote the postoperative recovery of patients; however, no specific treatment plan has been approved to enhance lung rehabilitation. Therefore, it is necessary to explore methods to promote the postoperative rehabilitation of patients with lung cancer. The patients with lung cancer who were admitted to Banan Hospital Affiliated to Chongqing Medical University (Chongqing, China) between January 2022 and January 2023, and who planned to undergo a thoracoscopic lobectomy, were randomly categorized into two groups. The experimental group began lung rehabilitation training 2 weeks before the operation and received individualized nutrition programs. The control group did not receive lung rehabilitation training and nutrition programs. The quality of life, lung function, 6-min walking distance (6MWD), nutritional status, postoperative complications, hospital expenses and hospital stay between the two groups were compared. Finally, 86 and 83 patients were included in the test and control groups, respectively. Regarding the postoperative indicators, the patients in the test group scored higher in all areas of quality of life, exhibited higher lung function and 6MWD, and had significantly higher serum total protein, albumin and hemoglobin levels, and body mass index, compared with the control group. Furthermore, the incidence of postoperative pulmonary complications, the duration of hospitalization and the hospitalization costs were lower in the experimental group. In conclusion, lung rehabilitation training combined with nutritional intervention can promote the postoperative rehabilitation of patients with lung cancer. The research has been duly registered in the Chinese Clinical Trial Register platform (registration no. ChiCTR2300078681; registered Dec 15, 2023).
胸腔镜肺叶切除术是肺癌外科治疗的主要方式。术后患者会出现并发症且肺功能下降,这影响了他们的出院时间和生活质量。肺通气训练已被证明可促进患者术后恢复;然而,尚未有获批的具体治疗方案来加强肺康复。因此,有必要探索促进肺癌患者术后康复的方法。将2022年1月至2023年1月期间入住重庆医科大学附属巴南医院(中国重庆)且计划接受胸腔镜肺叶切除术的肺癌患者随机分为两组。实验组在手术前2周开始肺康复训练并接受个性化营养方案。对照组未接受肺康复训练和营养方案。比较两组患者的生活质量、肺功能、6分钟步行距离(6MWD)、营养状况、术后并发症、住院费用和住院时间。最终,试验组和对照组分别纳入86例和83例患者。在术后指标方面,试验组患者在生活质量的各个方面得分更高,肺功能和6MWD更高,血清总蛋白、白蛋白和血红蛋白水平以及体重指数也显著高于对照组。此外,试验组术后肺部并发症的发生率、住院时间和住院费用更低。总之,肺康复训练联合营养干预可促进肺癌患者术后康复。该研究已在中国临床试验注册平台正式注册(注册号:ChiCTR2300078681;注册时间:20时)