Ayoub Samantha, Rajamohan Anandh G, Acharya Jay, Gross Jordan, Patel Vishal
Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Radiol Case Rep. 2020 Nov 28;16(2):237-240. doi: 10.1016/j.radcr.2020.11.017. eCollection 2021 Feb.
Gout is a common cause of inflammatory arthritis, typically affecting the joints of the appendicular skeleton. In this report, we present the relatively less common scenario of chronic tophaceous gout affecting the lumbar spine and pelvis, complicated by compressive neuropathy, and notable for its advanced initial presentation in a young patient. We review the pathophysiology underlying gout and discuss its clinical and laboratory presentation. We also use our case as an example to present the radiographic, CT, and MR imaging features of gout affecting the lumbar spine, which can often present a diagnostic dilemma. Finally, we discuss therapeutic options for gout resulting in spinal canal compromise, which include interventions not commonly performed for gout elsewhere in the body.
痛风是炎症性关节炎的常见病因,通常累及四肢骨骼的关节。在本报告中,我们介绍了一种相对少见的情况,即慢性痛风石性痛风累及腰椎和骨盆,并伴有压迫性神经病变,且该病例以年轻患者的晚期首发表现为显著特征。我们回顾了痛风的病理生理学,并讨论其临床和实验室表现。我们还以我们的病例为例,介绍了痛风累及腰椎的X线、CT和磁共振成像特征,这些特征常常会带来诊断难题。最后,我们讨论了导致椎管受压的痛风的治疗选择,其中包括一些在身体其他部位痛风中不常用的干预措施。