MercuŢ Irina-Maria, Ilia Louis-Claudiu, TĂnasie Cornelia-Andreea, Ionescu Mihaela, MercuŢ Razvan, PÎrvĂnescu Vlad, Ciurea Marius-Eugen
Department of Ophthalmology, University of Medicine and Pharmacy of Craiova, Romania.
Department of Bioinformatics and Biostatistics, University of Medicine and Pharmacy of Craiova, Romania.
Curr Health Sci J. 2020 Jul-Sep;46(3):222-229. doi: 10.12865/CHSJ.46.03.02. Epub 2020 Sep 30.
Almost 10% of worldwide skin cancers are located at the eyelid level. In European countries, malign eyelid tumours are mostly represented by basal and squamous cell carcinomas, and usually affect elderly patients. In order to study the clinical features of eyelid tumours, and potential correlations between tumour parameters, we have enrolled a cohort of 98 subjects from a south-western region of Romania. Our study confirmed the majority of results from other European studies, as basal cell carcinoma was the most frequent malign form, being diagnosed for more than 85% of patients with declared prolonged sun exposure; tumours were mostly located on the superior eyelid, especially for males, and may present slow progression rates. We have identified significant correlations only between the tumour stage and symptoms' duration, and also between the tumour stage and smoking habit, for females.
全球近10%的皮肤癌发生在眼睑部位。在欧洲国家，恶性眼睑肿瘤大多为基底细胞癌和鳞状细胞癌，通常影响老年患者。为了研究眼睑肿瘤的临床特征以及肿瘤参数之间的潜在相关性，我们从罗马尼亚西南部地区招募了98名受试者组成一个队列。我们的研究证实了其他欧洲研究的大部分结果，基底细胞癌是最常见的恶性形式，超过85%宣称长期暴露于阳光下的患者被诊断为此病；肿瘤大多位于上眼睑，男性尤为如此，且进展速度可能较慢。我们仅发现肿瘤分期与症状持续时间之间存在显著相关性，女性中肿瘤分期与吸烟习惯之间也存在显著相关性。
