Dinescu Sorin Nicolae, Vasile Ramona Constantina, FrunzulicĂ Maria Marilena, Dinescu Venera Cristina, Burada Emilia, TĂnasie Andreea, BicĂ CĂtĂlina Elena, Gheorman Victor, Georgescu Ovidiu Ştefan, Romanescu Florin Marius
Epidemiology Department, University of Medicine and Pharmacy of Craiova, Romania.
PhD, University of Medicine and Pharmacy of Craiova, Romania.
Curr Health Sci J. 2020 Jul-Sep;46(3):285-289. doi: 10.12865/CHSJ.46.03.10. Epub 2020 Sep 30.
Acute coronary events (ACE) are one of the main concerns for both clinical medicine and prophylaxis. The study aims to follow the frequency of the pathology associated with ACE and to establish its association with the occurrence of ACE. The study included 865 adult participants between the ages of 19-86. Subjects completed a complex questionnaire that included questions about health status. The study was conducted by applying the subjects to an anonymous questionnaire, in three family medicine practices between November 2018 to May 2019 and targeted healthy people. The frequencies of the following types of associated pathologies were evaluated: high blood pressure (HBP), hypercholesterolemia, stroke, diabetes, depression, stress. In hypertensive patients the prevalence of ACE was 6,99% (N=11) and in those not diagnosed with HBP of only 0,29% (N=2). The risk of ACE was 20 times higher than in those without HBP (RR=20,93; p<0.001). The prevalence of ACE was high among subjects with high cholesterol levels (21,43%) compared with those with normal values (3,03%; N=22), the risk of ACE being 7 times higher (RR=7,06; p<0.001). The prevalence of diabetes was more than four times higher in subjects with ACE (17,3%; N=9) compared with those without ACE (3,9%; N=32). Among those affected by diabetes, the prevalence of ACE was 21,95% (9/41), and risk of ACE in people with diabetes was four times higher (RR=4,21; p<0.001). Although cardiovascular disease is the most common pathology in the contemporary world, a number of comorbidities arise as ACE generators (hypertension, hypercholesterolemia, diabetes), along with psycho-emotional disorders such as depression, anxiety or stress, which outline, ensures, contributes or accelerates the progression to ACE.
急性冠脉事件（ACE）是临床医学和预防医学主要关注的问题之一。该研究旨在追踪与急性冠脉事件相关的病理情况的发生频率，并确定其与急性冠脉事件发生之间的关联。该研究纳入了865名年龄在19至86岁之间的成年参与者。受试者完成了一份综合问卷，其中包括有关健康状况的问题。该研究通过让受试者填写一份匿名问卷来进行，于2018年11月至2019年5月期间在三家家庭医学诊所开展，目标人群为健康人群。评估了以下几种相关病理情况的发生频率：高血压（HBP）、高胆固醇血症、中风、糖尿病、抑郁症、压力。在高血压患者中，急性冠脉事件的患病率为6.99%（N = 11），而在未被诊断为高血压的患者中仅为0.29%（N = 2）。急性冠脉事件的风险比未患高血压的患者高20倍（RR = 20.93；p < 0.001）。高胆固醇水平的受试者中急性冠脉事件的患病率较高（21.43%），而胆固醇值正常的受试者中患病率为3.03%（N = 22），急性冠脉事件的风险高7倍（RR = 7.06；p < 0.001）。与未发生急性冠脉事件的受试者（3.9%；N = 32）相比，发生急性冠脉事件的受试者中糖尿病的患病率高出四倍多（17.3%；N = 9）。在糖尿病患者中，急性冠脉事件的患病率为21.95%（9/41），糖尿病患者发生急性冠脉事件的风险高出四倍（RR = 4.21；p < 0.001）。尽管心血管疾病是当代世界最常见的病理情况，但一些合并症会引发急性冠脉事件（高血压、高胆固醇血症、糖尿病），同时还有心理情绪障碍，如抑郁症、焦虑症或压力，这些因素勾勒、确保、促成或加速了向急性冠脉事件的进展。
