Mueed Abdul, Khatti Shahzad, Ashraf Jibran, Aarij Khawaja M, Waqas Muhammad, Khan Tariq M
Cardiac Electrocardiography, National Institute of Cardiovascular Diseases, Karachi, PAK.
Interventional Cardiology, National Institute of Cardiovascular Diseases, Karachi, PAK.
Cureus. 2020 Nov 4;12(11):e11322. doi: 10.7759/cureus.11322.
Introduction Acute myocardial infarction (AMI) is a devastating medical emergency that requires immediate pharmacological and radiological intervention. With the advent of techniques such as percutaneous coronary intervention (PCI), pacemakers, and percussion pacing, survival rates have improved significantly. However, there are certain factors and complications associated with AMI that still lead to a high mortality rate, such as old age, advanced heart disease, diabetes mellitus (DM), and arrhythmias. Factors such as the type of arrhythmia, the heart rate, and the level at which dissociation occurs between atrial and ventricular rhythm all influence mortality and morbidity rates. Outcomes are further influenced by the sex of the patient, the type of AMI [ST-elevation myocardial infarction (STEMI) or non-ST-elevation myocardial infarction (NSTEMI)], history of smoking, arrival times at the hospital, presence of hyperglycemia, previous history of cardiac surgery, and the need for a temporary pacemaker or a permanent pacemaker. As with most scientific studies, local data from Pakistan is hard to find on this topic as well. With this study, we hope to contribute valuable information and updates to the study of a developing problem from the developing world. Objective We aimed to analyze the frequency and outcomes of different types of arrhythmia in AMI. Methods This study involved a retrospective observational cohort. It was conducted at the National Institute of Cardiovascular Diseases (NICVD), Karachi from January 2019 to July 2019 (six months). All data were retrieved from the online database at the NICVD. Written consent was obtained from all patients. Patient confidentiality was ensured at all times. Results A total of 500 patients were included in the study. The mean age of our cohort was 56.17 ±14.01 years. NSTEMI was more prevalent than STEMI. Sinus arrhythmia (SA) was the most frequently recorded arrhythmia and had the best survival rates. Atrioventricular (AV) nodal blocks and ventricular tachycardia (VT) had the worst outcomes. The overall mortality rate was 11.4%, and the mean in-hospital length of stay was 2.07 ±1.54 days. Smoking increased mortality in all cases. Conclusions AMI is complicated by several types of arrhythmia. SA is the most common arrhythmia in AMI. Mortality in AMI is largely due to AV nodal blocks and VT. Smoking increases mortality in all cases.
引言
急性心肌梗死(AMI)是一种严重的医疗急症,需要立即进行药物和放射学干预。随着经皮冠状动脉介入治疗(PCI)、起搏器和叩击起搏等技术的出现,生存率有了显著提高。然而,与AMI相关的某些因素和并发症仍然导致高死亡率,如老年、晚期心脏病、糖尿病(DM)和心律失常。心律失常的类型、心率以及心房和心室节律之间发生分离的水平等因素都会影响死亡率和发病率。患者的性别、AMI的类型[ST段抬高型心肌梗死(STEMI)或非ST段抬高型心肌梗死(NSTEMI)]、吸烟史、到达医院的时间、高血糖的存在、既往心脏手术史以及是否需要临时起搏器或永久起搏器等因素进一步影响预后。与大多数科学研究一样,关于这个主题的巴基斯坦本地数据也很难找到。通过这项研究,我们希望为来自发展中世界的一个正在发展的问题的研究贡献有价值的信息和更新。
目的
我们旨在分析AMI中不同类型心律失常的发生率和预后。
方法
本研究为回顾性观察队列研究。于2019年1月至2019年7月(六个月)在卡拉奇的国家心血管疾病研究所(NICVD)进行。所有数据均从NICVD的在线数据库中检索。获得了所有患者的书面同意。始终确保患者的保密性。
结果
共有500名患者纳入研究。我们队列的平均年龄为56.17±14.01岁。NSTEMI比STEMI更常见。窦性心律失常(SA)是最常记录到的心律失常,生存率最高。房室(AV)传导阻滞和室性心动过速(VT)的预后最差。总死亡率为11.4%,平均住院时间为2.07±1.54天。吸烟在所有情况下都会增加死亡率。
结论
AMI并发多种类型的心律失常。SA是AMI中最常见的心律失常。AMI的死亡率主要归因于AV传导阻滞和VT。吸烟在所有情况下都会增加死亡率。