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本文引用的文献

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Adolescent polycystic ovary syndrome according to the international evidence-based guideline.青少年多囊卵巢综合征的国际循证指南。
BMC Med. 2020 Mar 24;18(1):72. doi: 10.1186/s12916-020-01516-x.
2
Mental health conditions in bereaved military service widows: A prospective, case-controlled, and longitudinal study.丧夫军属的心理健康状况:一项前瞻性、病例对照和纵向研究。
Depress Anxiety. 2020 Jan;37(1):45-53. doi: 10.1002/da.22971. Epub 2019 Nov 25.
3
MANAGEMENT OF ENDOCRINE DISEASE: Morbidity in polycystic ovary syndrome.内分泌疾病管理:多囊卵巢综合征的发病情况。
Eur J Endocrinol. 2017 Feb;176(2):R53-R65. doi: 10.1530/EJE-16-0373. Epub 2016 Sep 6.
4
Naltrexone HCI/bupropion HCI for chronic weight management in obese adults: patient selection and perspectives.盐酸纳曲酮/盐酸安非他酮用于肥胖成年人的慢性体重管理:患者选择与观点
Patient Prefer Adherence. 2016 May 4;10:751-9. doi: 10.2147/PPA.S84778. eCollection 2016.
5
Psychiatric comorbidity in women with polycystic ovary syndrome.多囊卵巢综合征女性的精神共病
J Obstet Gynaecol Res. 2015 Aug;41(8):1229-33. doi: 10.1111/jog.12696. Epub 2015 Apr 1.
6
Bupropion and naltrexone: a review of their use individually and in combination for the treatment of obesity.安非他酮与纳曲酮:单独及联合使用治疗肥胖症的综述
Expert Opin Pharmacother. 2009 Apr;10(6):1069-81. doi: 10.1517/14656560902775750.
7
Women with polycystic ovary syndrome are often depressed or anxious--a case control study.多囊卵巢综合征女性常伴有抑郁或焦虑——一项病例对照研究。
Psychoneuroendocrinology. 2008 Sep;33(8):1132-8. doi: 10.1016/j.psyneuen.2008.06.003. Epub 2008 Jul 30.
8
Risk of depression and other mental health disorders in women with polycystic ovary syndrome: a longitudinal study.多囊卵巢综合征女性患抑郁症及其他心理健康障碍的风险:一项纵向研究
Fertil Steril. 2009 Jan;91(1):207-12. doi: 10.1016/j.fertnstert.2007.11.022. Epub 2008 Feb 4.
9
Depression, chronic diseases, and decrements in health: results from the World Health Surveys.抑郁症、慢性病与健康状况下降:世界卫生调查结果
Lancet. 2007 Sep 8;370(9590):851-8. doi: 10.1016/S0140-6736(07)61415-9.
10
Quality of life and psychological well being in polycystic ovary syndrome.多囊卵巢综合征患者的生活质量与心理健康
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安非他酮和纳曲酮在治疗多囊卵巢综合征伴发抑郁症中的作用:一例病例报告及文献综述

Role of Bupropion and Naltrexone in Managing Depression With Polycystic Ovary Syndrome: A Case Report and Literature Review.

作者信息

Shah Kaushal, Kulkarni Ritu, Singh Romil, Pannu Harmandeep S, Kamrai Dhwani

机构信息

Psychiatry, Griffin Memorial Hospital, Norman, USA.

Psychology, University of Oklahoma, Norman, USA.

出版信息

Cureus. 2020 Nov 5;12(11):e11343. doi: 10.7759/cureus.11343.

DOI:10.7759/cureus.11343
PMID:33304679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7719465/
Abstract

Polycystic ovary syndrome (PCOS) is a common endocrine disorder that affects women of reproductive age. Women with PCOS may present with obesity, amenorrhea, oligomenorrhea, infertility, or androgenic features. Studies have shown the association of psychiatric disorders with endocrine disorders, including PCOS. We present a case of a PCOS patient with no prior psychiatric history who presented with suicidal ideation. We emphasize the importance of screening women for PCOS when presented with mental disorders through this clinical case. It is crucial to rule out any medical causes in patients predominantly presented with psychiatric symptoms. We highlight the possible role of bupropion and naltrexone in managing PCOS symptoms, depression with suicidal ideation, and trichotillomania through this unique and rare case.

摘要

多囊卵巢综合征(PCOS)是一种常见的内分泌紊乱疾病,影响育龄女性。患有PCOS的女性可能出现肥胖、闭经、月经过少、不孕或雄激素过多的特征。研究表明,精神障碍与包括PCOS在内的内分泌紊乱有关。我们报告一例既往无精神病史的PCOS患者出现自杀意念的病例。通过这个临床病例,我们强调在女性出现精神障碍时筛查PCOS的重要性。对于主要表现为精神症状的患者,排除任何医学原因至关重要。通过这个独特而罕见的病例,我们强调安非他酮和纳曲酮在管理PCOS症状、伴有自杀意念的抑郁症和拔毛癖方面可能发挥的作用。