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儿童炎症性肠病的肺部表现

Pulmonary Manifestations of Inflammatory Bowel Disease in Children.

作者信息

Taylor Mark A, Zhou Holly, Dansie David M, Short Scott

机构信息

Department of Surgery, University of Utah, Salt Lake City, USA.

Department of Pathology, University of Utah, Salt Lake City, USA.

出版信息

Cureus. 2020 Nov 7;12(11):e11369. doi: 10.7759/cureus.11369.

Abstract

The recognition of pulmonary manifestations of inflammatory bowel disease (IBD) is important as these diseases can be confused with infectious etiologies (e.g., tuberculosis or fungal infection) and, as a result, may unnecessarily delay institution of appropriate therapy (e.g., infliximab). Furthermore, they are a source of morbidity that may be overlooked and, like other IBD-related pathologies, are often responsive to treatment with corticosteroids, immunomodulators, or biologic therapies. The purpose of this paper is to describe the cases of six children at a single institution with differing presentations, treatments, and responses to treatment of their IBD-related lung disease to improve recognition of this uncommon process.

摘要

认识炎症性肠病(IBD)的肺部表现很重要,因为这些疾病可能与感染性病因(如结核病或真菌感染)相混淆,结果可能会不必要地延迟适当治疗(如英夫利昔单抗)的开始。此外,它们是一种可能被忽视的发病原因,并且与其他IBD相关病理一样,通常对皮质类固醇、免疫调节剂或生物疗法有反应。本文的目的是描述在单一机构中6名儿童的病例,他们的IBD相关肺部疾病有不同的表现、治疗方法及治疗反应,以提高对这一罕见病程的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87eb/7721074/e35d4b7bdd61/cureus-0012-00000011369-i01.jpg

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