Jiang Jeffrey, Chang Stephanie H, Kent Amie J, Geraci Travis C, Cerfolio Robert J
Department of Cardiothoracic Surgery, New York University Langone Health, New York, NY, United States.
Front Surg. 2020 Nov 16;7:596925. doi: 10.3389/fsurg.2020.596925. eCollection 2020.
Screening for lung cancer has changed substantially in the past decade since The National Lung Screening Trial. The resultant increased discovery of incidental pulmonary nodules has led to a growth in the number of lesions requiring tissue diagnosis. Bronchoscopy is one main modality used to sample lesions, but peripheral lesions remain challenging for bronchoscopic biopsy. Alternatives have included transthoracic biopsy or operative biopsy, which are more invasive and have a higher morbidity than bronchoscopy. In hopes of developing less invasive diagnostic techniques, technologies have come to assist the bronchoscopist in reaching the outer edges of the lung. Navigational bronchoscopy is able to virtually map the lung and direct the biopsy needle where the scope cannot reach. Robotic bronchoscopy platforms have been developed to provide stability and smaller optics to drive deeper into the bronchial tree. While these new systems have not yet proven better outcomes, they may reduce the need for invasive procedures and be valuable armamentarium in diagnosing and treating lung nodules, especially in the periphery.
自国家肺癌筛查试验以来,过去十年间肺癌筛查发生了重大变化。由此导致的偶然发现的肺结节数量增加,使得需要进行组织诊断的病变数量增多。支气管镜检查是用于采集病变样本的主要方法之一,但对于周围性病变,支气管镜活检仍具有挑战性。替代方法包括经胸活检或手术活检,这些方法比支气管镜检查更具侵入性,发病率也更高。为了开发侵入性较小的诊断技术,已出现一些技术来协助支气管镜医师到达肺的外缘。导航支气管镜能够虚拟绘制肺部地图,并将活检针引导至支气管镜无法到达的部位。已开发出机器人支气管镜平台,以提供稳定性和更小的光学设备,从而更深入地进入支气管树。虽然这些新系统尚未证明能带来更好的结果,但它们可能会减少对侵入性手术的需求,并且在诊断和治疗肺结节,尤其是周围性肺结节方面,可能是有价值的手段。