Department of Otorhinolaryngology - Head and Neck Surgery, College of Medicine, Dankook Univeristy, Dankook University Hospital, Cheonan, Republic of Korea.
Acta Otolaryngol. 2021 Mar;141(3):261-266. doi: 10.1080/00016489.2020.1847322. Epub 2020 Dec 11.
There has been no report on the predictive value of auditory steady-state response (ASSR) in the hearing prognosis of sudden sensorineural hearing loss (SSNHL).
AIMS/OBJECTIVES: To investigate whether ASSR can be a prognostic indicator of hearing outcome in patients with SSNHL after systemic steroid treatment.
Fifty-three patients with unilateral mild to severe SSNHL (≤90 dB HL at 0.5k, 1k, 2k, and 4 kHz, 4FA) were included. All patients received systemic high dose steroid therapy within one month after onset. The difference between the threshold levels measured by ASSR and PTA on the same day [ASSR - PTA] was calculated. The hearing recovery (HR) was defined as < 30 dB HL of final degree of hearing loss and > 15 dB HL of hearing gain.
The HR (+) group showed significantly worse ASSR predicted threshold than pure-tone threshold in univariate ((51) = 2.412, = .020) and multivariate analysis (OR 0.910, = .012). The [ASSR - PTA] threshold showed significantly moderate correlation with hearing gain ( = -0.303, = .028).
Worse ASSR predicted threshold than pure-tone threshold predicted poor hearing outcome after systemic steroid treatment in mild to severe unilateral SSNHL.
目前尚无关于听觉稳态反应（ASSR）在突发性聋（SSNHL）听力预后预测中的价值的报告。
目的/目标：旨在探讨 ASSR 是否可作为 SSNHL 患者接受全身类固醇治疗后听力预后的预测指标。
共纳入 53 例单侧轻至重度 SSNHL（0.5k、1k、2k 和 4k Hz、4FA 处阈值≤90dB HL）患者。所有患者均在发病后 1 个月内接受全身大剂量类固醇治疗。计算 ASSR 与同日纯音听阈（PTA）测量值之间的差值[ASSR-PTA]。听力恢复（HR）定义为最终听力损失程度下降 < 30dB HL 和听力增益 > 15dB HL。
单因素分析（(51) = 2.412， = .020）和多因素分析（OR 0.910， = .012）均显示 HR（+）组 ASSR 预测阈值明显差于纯音听阈。[ASSR-PTA]阈值与听力增益呈显著中度相关（ = -0.303， = .028）。
在轻至重度单侧 SSNHL 患者中，全身类固醇治疗后 ASSR 预测阈值差于纯音听阈预测听力预后不良。
