Cardiovascular Surgery Division, Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (InCor-HCFMUSP), São Paulo, SP, Brazil.
Hospital Israelita Albert Einstein - Pavilhão Vick e Joseph Safra, São Paulo, SP, Brazil.
Braz J Cardiovasc Surg. 2020 Dec 1;35(6):986-989. doi: 10.21470/1678-9741-2020-0506.
Since Barnard's first heterotopic heart transplant in 1974, Copeland's method has been the greatest contribution to heterotopic transplants but has the drawback of donor's right ventricular atrophy. This new method proposes a modification in the anastomosis of the superior vena cava aiming to pre-serve donor's right ventricular function by decompressing the pulmonary territory and reducing the pulmonary arterial pressure, as a biological ventricular assist device. Finally, a second intervention is proposed, where a "twist" is performed to place the donor's heart in an orthotopic position after re-moval of the native heart. A pioneering research on this method received approval from the ethics committee of the Heart Institute of São Paulo. We believe that this method has the potential to im-prove quality of life in a selected group of patients.
自 1974 年 Barnard 首次进行异位心脏移植以来，Copeland 的方法是异位移植的最大贡献，但存在供体右心室萎缩的缺点。这种新方法提出了对上腔静脉吻合的修改，旨在通过减轻肺区的压力和降低肺动脉压来保护供体的右心室功能，作为一种生物心室辅助装置。最后，提出了第二次干预措施，在移除原生心脏后，通过“扭转”将供体心脏置于原位。该方法的一项开创性研究获得了圣保罗心脏研究所伦理委员会的批准。我们相信，这种方法有可能改善选定患者的生活质量。
