Sleptsov V P, Astakhov A A, Slezkin G A, Kharchenko D M
Vestn Khir Im I I Grek. 1987 Oct;139(10):75-8.
Metronidazole was used for treatment of 212 patients with peritonitis of appendicular origin. It resulted in lowered leukocytosis, elimination of the stab neutrophil shift, earlier reduction of the leukocyte intoxication index. The amount of suppurations of postoperative wounds decreased from 17% to 4.3%. The amount of reoperations was 2.4% instead of 5.4%. Metronidazole is recommended for treatment of acute appendicitis complicated by peritonitis.
甲硝唑用于治疗212例阑尾源性腹膜炎患者。它使白细胞增多症减轻,杆状核中性粒细胞左移消失,白细胞中毒指数更早降低。术后伤口化脓量从17%降至4.3%。再次手术量为2.4%,而非5.4%。推荐使用甲硝唑治疗并发腹膜炎的急性阑尾炎。