Bharucha N E, Bharucha E P, Dastur H D, Schoenberg B S
Neuroepidemiology Department, Bombay Hospital, India.
Am J Prev Med. 1987 Sep-Oct;3(5):293-9.
There is a paucity of trained neurologists in developing countries. We designed a questionnaire to rapidly screen a community of 851 people (Parsis living in a colony in Bombay, India) for possible neurologic diseases. This questionnaire was pretested and found to have a sensitivity of 100 percent for detecting epilepsy, febrile seizures (only in children), completed stroke, peripheral neuropathy, movement disorders, cerebral palsy, mental retardation, and severe dementia. The screening questionnaire was administered by trained lay health workers. One hundred and sixty-three people were identified by this questionnaire as possibly having neurologic disease. Neurologists later examined these 163 people and found that 80 of them actually suffered from at least one of the neurologic diseases of interest (positive predictive value = 48 percent). The most common neurologic disorders were peripheral neuropathy (32 cases), essential tremor (13 cases), stroke (12 cases), Parkinson's disease (six cases), and epilepsy (four cases).
发展中国家缺乏训练有素的神经科医生。我们设计了一份问卷,用于快速筛查一个由851人组成的社区(居住在印度孟买一个殖民地的帕西人)是否可能患有神经系统疾病。这份问卷经过了预测试,发现对于检测癫痫、热性惊厥(仅在儿童中)、完全性中风、周围神经病变、运动障碍、脑瘫、智力迟钝和严重痴呆,其敏感性为100%。筛查问卷由经过培训的非专业卫生工作者进行发放。通过这份问卷,有163人被确定可能患有神经系统疾病。神经科医生随后对这163人进行了检查,发现其中80人实际上患有至少一种感兴趣的神经系统疾病(阳性预测值 = 48%)。最常见的神经系统疾病是周围神经病变(32例)、特发性震颤(13例)、中风(12例)、帕金森病(6例)和癫痫(4例)。