School of Biomedical Engineering & Imaging Sciences, Kings College London, United Kingdom.
Guy's & St Thomas' Hospitals, London, United Kingdom.
Semin Musculoskelet Radiol. 2020 Dec;24(6):726-750. doi: 10.1055/s-0040-1719018. Epub 2020 Dec 11.
Whole-body magnetic resonance imaging (WB-MRI) is gradually being integrated into clinical pathways for the detection, characterization, and staging of malignant tumors including those arising in the musculoskeletal (MSK) system. Although further developments and research are needed, it is now recognized that WB-MRI enables reliable, sensitive, and specific detection and quantification of disease burden, with clinical applications for a variety of disease types and a particular application for skeletal involvement. Advances in imaging techniques now allow the reliable incorporation of WB-MRI into clinical pathways, and guidelines recommending its use are emerging. This review assesses the benefits, clinical applications, limitations, and future capabilities of WB-MRI in the context of other next-generation imaging modalities, as a qualitative and quantitative tool for the detection and characterization of skeletal and soft tissue MSK malignancies.
全身磁共振成像（WB-MRI）逐渐被整合到恶性肿瘤的检测、特征描述和分期的临床路径中，包括肌肉骨骼（MSK）系统中的肿瘤。尽管需要进一步的发展和研究，但现在已经认识到 WB-MRI 能够可靠、敏感和特异性地检测和量化疾病负担，具有多种疾病类型的临床应用，特别是骨骼受累的应用。成像技术的进步现在允许可靠地将 WB-MRI 纳入临床路径，并且正在出现推荐其使用的指南。本综述评估了 WB-MRI 在其他下一代成像方式背景下的优势、临床应用、局限性和未来功能，作为一种用于检测和特征描述骨骼和软组织 MSK 恶性肿瘤的定性和定量工具。
