Department of Ophthalmology, Hangil Eye Hospital, Incheon, Korea.
Korean J Ophthalmol. 2020 Dec;34(6):462-468. doi: 10.3341/kjo.2020.0085. Epub 2020 Dec 3.
To evaluate the effect of intraocular pressure (IOP)-lowering medications on myopic retinoschisis.
The medical records of 33 patients (36 eyes) with myopic retinoschisis associated with pathologic myopia were reviewed retrospectively. The patients were divided into two groups: the study group comprising patients undergoing treatment with anti-glaucoma medications for suspected glaucoma; the control group comprising patients who did not use any IOP lowering medications. The changes in retinoschisis in the two groups were compared using the Spectralis domain optical coherence tomography thickness map protocol.
The study group included 18 eyes (17 patients), and the control group included 18 eyes (16 patients). There were no significant differences between the 6-month and 12-month improvement or aggravation rates of the two groups (p = 0.513 and 0.137, respectively). However, after 18 months, the aggravation rate of retinoschisis was significantly lower in the study group (p = 0.003). The improvement / aggravation rate was 58.33% / 16.67% in the study group and 0% / 57.14% in the control group.
The use of IOP-lowering medications for more than a year may be useful for the management of retinoschisis associated with pathologic myopia.
评估眼压降低药物对近视性视网膜劈裂的影响。
回顾性分析 33 例（36 只眼）病理性近视伴近视性视网膜劈裂患者的病历资料。将患者分为两组：研究组为疑似青光眼患者使用抗青光眼药物治疗；对照组为未使用任何降眼压药物的患者。采用 Spectralis 域光学相干断层扫描厚度图方案比较两组视网膜劈裂的变化。
研究组包括 17 例（18 只眼），对照组包括 16 例（18 只眼）。两组患者在 6 个月和 12 个月时改善或加重的比例无显著差异（p = 0.513 和 0.137）。然而，18 个月后，研究组视网膜劈裂加重的比例显著降低（p = 0.003）。研究组的改善/加重率为 58.33%/16.67%，对照组为 0%/57.14%。
使用降眼压药物超过 1 年可能有助于病理性近视伴视网膜劈裂的管理。
