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经支气管镜肺减容术:土耳其三级医疗中心的研究结果。

Endobronchial valve vs coil for lung volume reduction in emphysema: results from a tertiary care centre in Turkey.

机构信息

From the Department of Chest Surgery, Afyonkarahisar University of Health Sciences, Afyonkarahisar, Turkey.

From the Department of Chest Surgery, Acibadem Hospitals Group, Kayseri, Turkey.

出版信息

Ann Saudi Med. 2020 Nov-Dec;40(6):469-476. doi: 10.5144/0256-4947.2020.469. Epub 2020 Dec 3.

DOI:10.5144/0256-4947.2020.469
PMID:33307740
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7733646/
Abstract

BACKGROUND

Bronchoscopic lung volume reduction (BLVR) by either the endobronchial valve (EBV) or coil (EBC) procedure is recommended for severe emphysematous patients. BLVR applications generally help healthy lung areas ventilate more comfortably by reducing the hyperinflation and improving the contraction capacity of diaphragm.

OBJECTIVES

Compare our experience with valve and coil BLVR devices.

DESIGN

Retrospective.

SETTING

Single tertiary care centre.

PATIENTS AND METHODS

Demographic data, vital signs, pulmonary function tests (PFTs), the six-minute walking test (6MWT), vital signs, arterial blood gases and complications were recorded.

MAIN OUTCOME MEASURES

Change in PFTs and completion of the 6MWT.

SAMPLE SIZE

60 Turkish men with a diagnosis of chronic pulmonary lung disease.

RESULTS

Clinical and demographic characteristics were similar in patients who underwent EBV and EBC. Thirty (96.8%) EBV patients and 27 (93.1%) of the EBC patients were able to properly complete the PFT before the procedures, but all complied after the procedures. Significant improvement in PFTs were achieved after the procedure and there were no statistically significant differences in post-procedure performance. For the 6MWT, the completion rate improved from 15 (48.4%) to 19 (61.3%) patients in the EBV patients (=.125) and from 19 (65.5%) to 21 (72.4%) patients in the EBC patients (=.500). There was no significant difference in completion rates for the walking test for either group (median 32 meters in EBV patients and 37 meters in EBC patients; =.652). Vital signs and arterial blood gases were similar in the two groups. The rates of complications were similar in both groups.

CONCLUSION

Endobronchial valves and coils are safe and effective methods for BLVR for patients with severe emphysema.

LIMITATIONS

Relatively small sample, retrospective design, single-centre retrospective study.

CONFLICT OF INTEREST

None.

摘要

背景

支气管镜肺减容术(BLVR)通过支气管内阀(EBV)或线圈(EBC)程序,推荐用于严重肺气肿患者。BLVR 应用通常通过减少过度充气和改善膈肌收缩能力来帮助健康的肺区域更舒适地通气。

目的

比较我们在瓣膜和线圈 BLVR 装置方面的经验。

设计

回顾性。

设置

单一的三级保健中心。

患者和方法

记录人口统计学数据、生命体征、肺功能检查(PFTs)、六分钟步行试验(6MWT)、生命体征、动脉血气和并发症。

主要观察指标

PFTs 的变化和 6MWT 的完成情况。

样本量

60 名土耳其男性慢性肺部疾病患者。

结果

接受 EBV 和 EBC 的患者的临床和人口统计学特征相似。30 名(96.8%)EBV 患者和 27 名(93.1%)EBC 患者在手术前能够正确完成 PFT,但所有患者在手术后都能完成。手术后 PFTs 显著改善,术后表现无统计学差异。对于 6MWT,EBV 患者的完成率从 15 名(48.4%)提高到 19 名(61.3%)(= 0.125),EBC 患者的完成率从 19 名(65.5%)提高到 21 名(72.4%)(= 0.500)。两组步行试验的完成率无显著差异(中位数 EBV 患者为 32 米,EBC 患者为 37 米;= 0.652)。两组生命体征和动脉血气相似。两组并发症发生率相似。

结论

支气管内瓣膜和线圈是治疗严重肺气肿患者 BLVR 的安全有效方法。

局限性

样本量相对较小,回顾性设计,单中心回顾性研究。

利益冲突

无。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a1/7733646/bcfd37d461b0/0256-4947.2020.469-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a1/7733646/55925b3228a4/0256-4947.2020.469-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a1/7733646/9f754115c1c9/0256-4947.2020.469-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a1/7733646/bcfd37d461b0/0256-4947.2020.469-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a1/7733646/55925b3228a4/0256-4947.2020.469-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a1/7733646/9f754115c1c9/0256-4947.2020.469-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a1/7733646/bcfd37d461b0/0256-4947.2020.469-fig3.jpg

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