Department of Nursing, Xi'an International Medical Center Hospital, East of Xitai Road, High-tech Zone, Xi'an, 329000, Shaanxi Province, China.
BMC Infect Dis. 2020 Dec 11;20(1):949. doi: 10.1186/s12879-020-05630-2.
Intracranial infection after puncture of cerebral hematoma in patients with intracerebral hemorrhage is very common in the department of neurosurgery, yet the relevant risks remain unknown. We attempted to analyze the risk factors of intracranial infection after puncture of cerebral hematoma, to provide insights into the management of patients with intracerebral hemorrhage after puncture of cerebral hematoma.
Patients with intracerebral hemorrhage after puncture of cerebral hematoma treated in our hospital from January 2017 to January 2020 were selected, the related characteristics of intracranial infection and no infection patients were compared. Logistic regression analyses were conducted to analyze the risk factors for intracranial infection after puncture of cerebral hematoma.
A total of 925 patients with puncture of cerebral hematoma were included. The incidence of postoperative intracranial infection was 7.03%. There were significant statistical differences between the infected group and the no infection group in the American Association of Anesthesiologists (ASA) grade, length of hospital stay, consecutive operation, duration of surgery, extra-ventricular drainage (EVD) use (all p < 0.05). There was statistically significant difference in the duration of EVD between the infection and no infection groups (p = 0.002), and there was no significant difference in the frequency of EVD insertion between the two groups (p = 0.094). The length of hospital stay≥10 days (OR1.832, 1.062-3.158), consecutive operation (OR2.158, 1.358-3.430), duration of surgery≥4 h (OR1.581, 1.031-2.425), EVD use (OR1.694, 1.074-2.670), and duration of EVD ≥ 7 days (OR2.699, 1.689-4.311) were the risk factors of intracranial infection in patients with intracerebral hemorrhage after puncture of cerebral hematoma (all p < 0.05).
Clinical medical workers should take corresponding preventive measures against the different risk factors for prevention of intracranial infection in patient with puncture of cerebral hematoma.
脑出血患者血肿穿刺后颅内感染在神经外科非常常见，但相关风险尚不清楚。我们试图分析血肿穿刺后颅内感染的危险因素，为脑出血患者血肿穿刺后管理提供参考。
选取我院 2017 年 1 月至 2020 年 1 月收治的脑出血血肿穿刺患者，比较颅内感染和无感染患者的相关特征。采用 logistic 回归分析血肿穿刺后脑内感染的危险因素。
共纳入 925 例血肿穿刺患者，术后颅内感染发生率为 7.03%。感染组与无感染组在 ASA 分级、住院时间、连续手术、手术时间、使用外引流（EVD）（均 P<0.05）方面有统计学差异。感染组与无感染组 EVD 使用时间（P=0.002）有统计学差异，EVD 插入次数无统计学差异（P=0.094）。住院时间≥10 d（OR1.832，1.062-3.158）、连续手术（OR2.158，1.358-3.430）、手术时间≥4 h（OR1.581，1.031-2.425）、使用 EVD（OR1.694，1.074-2.670）、EVD 使用时间≥7 d（OR2.699，1.689-4.311）是脑出血患者血肿穿刺后颅内感染的危险因素（均 P<0.05）。
临床医务人员应针对脑出血患者血肿穿刺后颅内感染的不同危险因素采取相应的预防措施。
