Suzuki N, Mizukoshi T
Department of Radiation Oncology, Faculty of Medicine, University of Tokyo, Japan.
Radiat Med. 1987 Nov-Dec;5(6):212-4.
The effect of low-dose (10-50 cGy) irradiation, delivered as single or fractionated doses, on metastatic development was investigated using NFSA2ALM1 fibrosarcoma and the C3H/HeNrs mouse. Spontaneous lung metastases from tumors transplanted into the leg were suppressed in those mice irradiated with low doses of radiation 12 days after tumor cell inoculation. Abbreviations used: LCFE = lung colony forming efficiency through i.v. injection of tumor cells; SLME = spontaneous lung metastasis efficiency from leg tumors; TD50 = cell number which produces tumors in 50% of inoculated sites; WBI = Whole body irradiation.
使用NFSA2ALM1纤维肉瘤和C3H/HeNrs小鼠，研究了以单次或分次剂量给予的低剂量（10 - 50 cGy）辐射对转移发展的影响。在肿瘤细胞接种12天后接受低剂量辐射的小鼠中，移植到腿部的肿瘤的自发性肺转移受到抑制。使用的缩写：LCFE = 通过静脉注射肿瘤细胞的肺集落形成效率；SLME = 腿部肿瘤的自发性肺转移效率；TD50 = 在50%接种部位产生肿瘤的细胞数；WBI = 全身照射。
