一名患有重度特发性肺动脉高压的儿科患者的登革热疾病

Dengue disease in a pediatric patient with severe idiopathic pulmonary hypertension.

作者信息

Díaz Gabriel, Devia Claudia P, De La Hoz Orlando M

机构信息

Pediatric Cardiologist, Titular Professor, Department of Pediatrics, Universidad Nacional de Colombia, Fundación Santa Fe de Bogota, Bogota, Colombia.

Fellow of Neonatology, Universidad Nacional de Colombia, Bogota, Colombia.

出版信息

Cardiol Young. 2021 Apr;31(4):654-657. doi: 10.1017/S1047951120004321. Epub 2020 Dec 14.

DOI:10.1017/S1047951120004321

PMID:33308360

Abstract

Dengue virus can affect the heart, with complications as bradycardia, arrhythmias, and death. We present a case of a 15-year-old patient, diagnosed 4 years before with severe idiopathic pulmonary hypertension, confirmed by catheterism, with continuous follow up. At that time, she was living in Bogotá (2640 m above sea level). Sildenafil and Macitentan were started. She was recommended to live at low altitude and she moved. The patient was transferred back to Bogota, from that place, due to flu-like symptoms and fever. Immunoglobulin M for dengue was confirmed and second-degree atrioventricular block Mobitz I with bradycardia (40 beats/minute) was documented throughout the clinical course. She recovered.

摘要

登革热病毒可影响心脏，引发心动过缓、心律失常及死亡等并发症。我们报告一例15岁患者，4年前被诊断为重度特发性肺动脉高压，经心导管检查确诊，并持续接受随访。当时，她居住在波哥大（海拔2640米）。开始使用西地那非和马昔腾坦治疗。建议她居住在低海拔地区，随后她搬离了。该患者因出现类似流感的症状和发热，从那个地方转回了波哥大。登革热免疫球蛋白M检测呈阳性，整个临床过程记录显示存在二度莫氏I型房室传导阻滞伴心动过缓（每分钟40次心跳）。她最终康复。