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同伴对肥胖的影响:来自基因-环境相互作用自然实验的证据。

Peer influence on obesity: Evidence from a natural experiment of a gene-environment interaction.

作者信息

Li Yi, Guo Guang

机构信息

Department of Sociology, University of Macau, Macau, China.

Department of Sociology, University of North Carolina at Chapel Hill, USA; Carolina Population Center, University of North Carolina at Chapel Hill, USA; Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, USA.

出版信息

Soc Sci Res. 2021 Jan;93:102483. doi: 10.1016/j.ssresearch.2020.102483. Epub 2020 Oct 20.

DOI:10.1016/j.ssresearch.2020.102483
PMID:33308683
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8607809/
Abstract

The role of peers in explaining the obesity epidemic is difficult to evaluate, largely due to selection (the tendency of similar individuals to make friends with each other). Our study addresses this selection issue by using data from a natural experiment of randomly assigned college roommates. We investigate whether and how peers, gender, and the FTO gene interactively influenced BMI. We find that women with a weight-prone version of the gene were about three pounds lighter if assigned frequently-exercising roommates than if assigned non-frequently-exercising roommates. However, living with frequently-exercising roommates had little impact for women without the weight-prone version of the gene or for men regardless of genotype. We find that individuals with the weight-prone version of the gene exercised more often when assigned frequently-exercising roommates. This might be a mechanism through which the effect of frequently-exercising roommates worked.

摘要

同伴在解释肥胖流行现象中所起的作用很难评估,这主要是由于选择性因素(即相似的个体倾向于相互结交为朋友)。我们的研究通过使用来自一项随机分配大学室友的自然实验的数据来解决这一选择性问题。我们调查了同伴、性别和FTO基因是否以及如何交互影响体重指数(BMI)。我们发现,携带易胖型基因的女性若被分配到经常锻炼的室友,其体重比被分配到不经常锻炼的室友时轻约三磅。然而,对于没有易胖型基因的女性或无论基因型如何的男性而言,与经常锻炼的室友同住对他们的体重影响不大。我们发现,携带易胖型基因的个体在被分配到经常锻炼的室友时会更频繁地锻炼。这可能是经常锻炼的室友产生影响的一种机制。

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本文引用的文献

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Prevalence of Obesity and Severe Obesity Among Adults: United States, 2017-2018.成年人肥胖和重度肥胖的患病率:美国,2017-2018 年。
NCHS Data Brief. 2020 Feb(360):1-8.
2
Heterogeneous peer effects on marijuana use: Evidence from a natural experiment.大麻使用中的异质同伴效应:来自自然实验的证据。
Soc Sci Med. 2020 May;252:112907. doi: 10.1016/j.socscimed.2020.112907. Epub 2020 Mar 6.
3
Peer Influence on Aggressive Behavior, Smoking, and Sexual Behavior: A Study of Randomly-assigned College Roommates.同伴对攻击性行为、吸烟和性行为的影响:一项关于随机分配的大学室友的研究。
J Health Soc Behav. 2016 Sep;57(3):297-318. doi: 10.1177/0022146516661594.
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Body Fatness and Cancer--Viewpoint of the IARC Working Group.身体肥胖与癌症——国际癌症研究机构工作组的观点
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Gendering Genetics: Biological Contingencies in the Protective Effects of Social Integration for Men and Women.性别与遗传学:社会融合对男性和女性保护作用中的生物偶然性
AJS. 2016 May;121(6):1655-96. doi: 10.1086/685486.
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The Genetics of Success: How Single-Nucleotide Polymorphisms Associated With Educational Attainment Relate to Life-Course Development.成功的遗传学:与受教育程度相关的单核苷酸多态性如何与生命历程发展相关联。
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Am Sociol Rev. 2015 Aug;80(4):705-737. doi: 10.1177/0003122415590627.
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Peer Influence, Genetic Propensity, and Binge Drinking: A Natural Experiment and a Replication.同伴影响、遗传倾向与狂饮:一项自然实验及重复验证
AJS. 2015 Nov;121(3):914-54. doi: 10.1086/683224.
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Does Marriage Moderate Genetic Effects on Delinquency and Violence?婚姻是否会调节基因对犯罪和暴力行为的影响?
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