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使用低脉冲能量飞秒激光对中低度角膜散光患者行弓形角膜切开术的一年结果

One-Year Results of Arcuate Keratotomy in Patients With Low to Moderate Corneal Astigmatism Using a Low-Pulse-Energy Femtosecond Laser.

作者信息

Schwarzenbacher Luca, Schartmüller Daniel, Röggla Veronika, Meyer Elias, Leydolt Christina, Menapace Rupert

机构信息

Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.

Section for Medical Statistics, Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria.

出版信息

Am J Ophthalmol. 2021 Apr;224:53-65. doi: 10.1016/j.ajo.2020.11.018. Epub 2020 Dec 9.

DOI:10.1016/j.ajo.2020.11.018
PMID:33309694
Abstract

PURPOSE

To investigate corneal astigmatism (CA) reduction and corneal optical quality after surface-penetrating femtosecond laser arcuate keratotomies (Femto AK) considering anterior (CA) and posterior corneal curvature (CA), total corneal refractive power astigmatism (CA), and corneal higher-order aberrations (HOAs) through 1 year.

DESIGN

Prospective interventional case series.

METHODS

Setting: Department of Ophthalmology, Medical University of Vienna. PatientPopulation: Forty-three eyes of 43 patients with age-related cataract and CA between 1 and 3 diopters (D).

INTERVENTION

Paired keratotomies were created with a low-energy femtosecond laser (LDV Z8; Ziemer Ophthalmic Systems, Port, Switzerland) and combined with an astigmatic neutral manual posterior-limbal cataract incision. CA and HOAs measurements were obtained preoperatively and after 1 month, 3 months, and 1 year. MainOutcomeMeasure: Change of CA and HOAs after low-energy Femto AK through 1 year.

RESULTS

Mean preoperative CA and CA (1.62 ± 0.49 D and 1.58 ± 0.44 D) were significantly reduced, to 0.66 ± 0.38 and 0.50 ± 0.30 D (P < .001) 1 year after surgery, respectively. CA showed no significant change, from 0.31 ± 0.19 D preoperatively to 0.31 ± 0.13 D (P = .732) at the 1-year follow-up period. Astigmatism as calculated by vector astigmatism analysis stayed stable at 1 month, 3 months, and 1 year. Corneal wavefront HOAs significantly improved at 1 month, 3 months, and 1 year.

CONCLUSIONS

Paired surface-penetrating keratotomies created by a low-energy femtosecond laser showed efficient and stable CA reduction within 1 year after surgery. The optical quality of the cornea was preserved with lower HOAs than preoperatively.

摘要

目的

通过为期1年的观察,研究穿透性飞秒激光弧形角膜切开术(飞秒AK)后角膜散光(CA)的降低情况以及角膜光学质量,其中考虑了前角膜散光(CA)和后角膜曲率散光(CA)、角膜总屈光力散光(CA)以及角膜高阶像差(HOAs)。

设计

前瞻性干预病例系列研究。

方法

地点:维也纳医科大学眼科。患者群体:43例年龄相关性白内障且角膜散光在1至3屈光度(D)之间的患者的43只眼。

干预措施

使用低能量飞秒激光(LDV Z8;齐默眼科系统公司,瑞士波特)进行配对角膜切开术,并联合散光中和手动后缘白内障切口。术前以及术后1个月、3个月和1年进行角膜散光和高阶像差测量。主要观察指标:低能量飞秒AK术后1年内角膜散光和高阶像差的变化。

结果

术后1年,术前平均角膜散光和角膜曲率散光(分别为1.62±0.49 D和1.58±0.44 D)显著降低,分别降至0.66±0.38 D和0.50±0.30 D(P<.001)。角膜总屈光力散光无显著变化,术前为0.31±0.19 D,1年随访期时为0.31±0.13 D(P = .732)。通过矢量散光分析计算的散光在1个月、3个月和1年时保持稳定。角膜波前高阶像差在1个月、3个月和1年时均显著改善。

结论

低能量飞秒激光进行的配对穿透性角膜切开术在术后1年内显示出有效且稳定的角膜散光降低效果。角膜的光学质量得以保留,且高阶像差低于术前。

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