Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig-Maximilians-Universität München, Munich, Germany.
Institute of Health Economics and Health Care Management, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany; Department of Economics, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Exp Gerontol. 2021 Mar;145:111196. doi: 10.1016/j.exger.2020.111196. Epub 2020 Dec 10.
We explored the male-female health-survival paradox in the context of health expectancy (HE) at age 65 and thereafter, using three different morbidity measures and different severity cut-offs with and without adjustments for the share of nursing home residents.
HE at ages 65, 70, 75, 80, and 85 was estimated with the Sullivan method, linking morbidity prevalence from the KORA (Cooperative Health Research in the Region of Augsburg)-Age study to 2016 Bavarian mortality data. Morbidity measures comprised deficit accumulation (Frailty Index, FI, cut-offs 0.08 and 0.25), disability (Health Assessment Questionnaire-Disability Index, HAQ-DI, cut-off >0) and participation (Global Activity Limitation Indicator, GALI, "limited" vs "not limited").
Morbidity data were available for 4083 participants (52.7% female). HE was lower in women than in men at all ages. Differences in morbidity prevalence, absolute HE, and health proportions of life expectancy (relative HE) increased with age for FI ≥ 0.25 and GALI, but not for HAQ-DI > 0 and FI > 0.08. Accounting for the share of nursing home residents resulted in a slight reduction of HE estimates but had no impact on estimated sex differences.
In HE at age 65 and thereafter, women's health disadvantage was larger than their life expectancy advantage over men.
我们探讨了在 65 岁及以后的健康预期寿命(HE)背景下,男性和女性的健康-生存悖论,使用了三种不同的发病率衡量标准和不同的严重程度临界点,同时还考虑了有无对养老院居民比例的调整。
使用 Sullivan 法估计了年龄在 65、70、75、80 和 85 岁时的 HE,该方法将 KORA(奥格斯堡地区合作健康研究)-Age 研究中的发病率流行率与 2016 年巴伐利亚州的死亡率数据联系起来。发病率衡量标准包括缺陷积累(衰弱指数,FI,临界点为 0.08 和 0.25)、残疾(健康评估问卷-残疾指数,HAQ-DI,临界点>0)和参与度(全球活动限制指标,GALI,“受限”与“无限制”)。
4083 名参与者(52.7%为女性)提供了发病率数据。在所有年龄段,女性的 HE 都低于男性。FI≥0.25 和 GALI 的发病率流行率、绝对 HE 和预期寿命的健康比例(相对 HE)的差异随着年龄的增长而增加,但对于 HAQ-DI>0 和 FI>0.08 则不是。考虑到养老院居民的比例,会略微降低 HE 的估计值,但对估计的性别差异没有影响。
在 65 岁及以后的 HE 中,女性的健康劣势大于其相对于男性的预期寿命优势。