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印度的小儿肝移植:22年且仍在继续。

Pediatric Liver Transplantation in India: 22 Years and Counting.

作者信息

Malhotra Smita, Sibal Anupam, Goyal Neerav

机构信息

Department of Pediatric Gastroenterology and Hepatology, Indraprastha Apollo Hospitals, New Delhi, India. Correspondence to: Dr Smita Malhotra, Department of Pediatric Gastroenterology and Hepatology, Apollo Institute of Pediatric Sciences, Indraprastha Apollo Hospital, New Delhi, India.

Department of Pediatric Gastroenterology and Hepatology, Indraprastha Apollo Hospitals, New Delhi, India.

出版信息

Indian Pediatr. 2020 Dec 15;57(12):1110-1113.

Abstract

Liver transplantation in India has grown exponentially in the last decade with 135 centers now performing between 1500-2000 transplants a year, 10% of which are pediatric. Survival rate surpassing 90% has been achieved, and India is now an important regional liver transplant hub in South and South-East Asia. The indications have expanded to include increasing number of liver-based metabolic disorders that may or may not cause liver disease. Recipients, who were previously considered non-transplantable such as those with pre-existing portal vein thrombosis, can be successfully managed with innovative microvascular techniques. The donor pool has grown with the use of marginal grafts and ABO incompatible organs. Financial constraints are being overcome by crowd funding and increasing philanthropic efforts.

摘要

在过去十年中,印度的肝脏移植数量呈指数级增长,目前有135个中心每年进行1500至2000例移植手术,其中10%是儿童移植。存活率已超过90%,印度现已成为南亚和东南亚重要的区域性肝脏移植中心。肝脏移植的适应证范围不断扩大,包括越来越多的可能导致或不导致肝脏疾病的肝脏代谢紊乱。以前被认为不可移植的受者,如那些已存在门静脉血栓形成的患者,现在可以通过创新的微血管技术成功治疗。随着边缘供肝和ABO血型不相容器官的使用,供肝库有所增加。众筹和慈善事业的增加正在克服资金方面的限制。

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