Krajewski Piotr K, Matusiak Łukasz, von Stebut Esther, Schultheis Michael, Kirschner Uwe, Nikolakis Georgios, Szepietowski Jacek C
Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, PL-51-165 Wrocław, Poland.
Acta Derm Venereol. 2021 Jan 5;101(1):adv00364. doi: 10.2340/00015555-3724.
Hidradenitis suppurativa is a chronic, inflammatory skin disorder that affects the pilosebaceous unit of the intertriginous body areas. Pain is one of the most important problems in patients with hidradenitis suppurativa. The aim of this study, which included 1,795 patients, was to evaluate the prevalence and characteristics of pain. The intensity of pain was assessed with a numerical rating scale. In addition, pain intensity was correlated with various clinical features. Pain was reported by 83.6% of subjects. The majority of patients (77.6%) experienced mild pain; women and smokers tended to experience more intense pain. Pain intensity was greater in patients with multiple affected skin areas and correlated positively with the number of those affected areas (r = 0.151, p < 0.001). There was no difference in pain intensity between affected locations. The worst pain was observed in the patients with the most severe disease and it would weaken significantly along with the severity of hidradenitis suppurativa (assessed using the Hurley staging system and the International Hidradenitis Suppurativa Severity Score System).
化脓性汗腺炎是一种慢性炎症性皮肤病，累及身体褶皱部位的毛囊皮脂腺单位。疼痛是化脓性汗腺炎患者最重要的问题之一。本研究纳入了1795例患者，旨在评估疼痛的患病率及特征。采用数字评定量表评估疼痛强度。此外，疼痛强度还与各种临床特征相关。83.6%的受试者报告有疼痛。大多数患者（77.6%）经历轻度疼痛；女性和吸烟者往往经历更剧烈的疼痛。多个皮肤区域受累的患者疼痛强度更大，且与受累区域数量呈正相关（r = 0.151，p < 0.001）。受累部位之间的疼痛强度没有差异。病情最严重的患者疼痛最剧烈，且随着化脓性汗腺炎病情严重程度（采用赫尔利分期系统和国际化脓性汗腺炎严重程度评分系统评估）的减轻，疼痛会显著缓解。
