Department of Forensic Psychiatry, University Hospital of Psychiatry Zurich, Zurich, Switzerland.
Computer Vision Laboratory, Department of Information Technology and Electrical Engineering, Swiss Federal Institute of Technology (ETH) Zurich, Zurich, Switzerland.
Int J Methods Psychiatr Res. 2021 Jun;30(2):e1856. doi: 10.1002/mpr.1856. Epub 2020 Dec 15.
People with schizophrenia show a higher risk of committing violent offenses. Previous studies indicate that there are at least three subtypes of offenders with schizophrenia.
Employing latent class analysis, the goals of this study were to investigate the presence of homogeneous subgroups of offender patients in terms of remission in psychopathology during inpatient treatment and whether or not these are related to subtypes found in previous studies. Results should help identify patient subgroups benefitting insufficiently from forensic inpatient treatment and allow hypotheses on possibly more suitable therapy option for these patients.
A series of latent class analyses was used to explore extensive and detailed psychopathological reports of 370 offender patients with schizophrenia before and after inpatient treatment.
A framework developed by Hodgins to identify subgroups of offenders suffering from schizophrenia is useful in predicting remission of psychopathology over psychiatric inpatient treatment. While "early starters" were most likely to experience remission of psychopathology over treatment, "late late starters" and a subgroup including patients from all three of Hodgins' subgroups in equal proportions benefited least. Negative symptoms generally seemed least likely to remit.
Psychiatric treatment may have to be more tailored to offender patient subgroups to allow them to benefit more equally.
精神分裂症患者有更高的暴力犯罪风险。先前的研究表明，精神分裂症患者的犯罪者至少有三个亚型。
本研究采用潜在类别分析，旨在调查在住院治疗期间精神病学缓解方面，罪犯患者是否存在同质亚组，以及这些亚组是否与先前研究中发现的亚型相关。研究结果有助于识别出从法医住院治疗中受益不足的患者亚组，并为这些患者提出更适合的治疗方案假设。
本研究使用了一系列潜在类别分析，以探索 370 名患有精神分裂症的罪犯患者住院治疗前后广泛而详细的精神病学报告。
Hodgins 用于识别患有精神分裂症的罪犯亚组的框架可用于预测精神病住院治疗期间精神病学缓解情况。虽然“早期启动者”最有可能在治疗过程中缓解精神病学症状，但“晚期晚期启动者”和包括 Hodgins 所有三个亚组患者的亚组受益最少。一般来说，阴性症状似乎最不可能缓解。
精神病治疗可能需要更针对罪犯患者亚组，以使他们能够更平等地受益。
