Department of Dermatology, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.
P R Health Sci J. 2020 Dec;39(4):306-310.
To describe the patient population with mycosis fungoides (MF) in Puerto Rico in terms of demographics, disease course, and management.
We performed a retrospective chart review of patients with MF who were being followed at the University of Puerto Rico dermatology clinics from 1999 through 2016. Collected data included demographics, age at diagnosis, stage at diagnosis, follow-up time, treatment, and stage at the time of the study.
A total of 53 patients were diagnosed with MF from 1999 through 2016, with a mean follow-up period of 89 months. Of those, 45% were male. At the time of diagnosis, 40% were at stage 1A, 53% were at stage 1B, and 7% were at stages 2 to 4. During data collection, 74% of the patients remained stable, 18% improved clinically, and 8% progressed in disease stage. The treatment modalities used included phototherapy, topical steroids, topical and systemic retinoids, methotrexate, topical and systemic chemotherapy, and interferon.
Our study reflects the chronic and indolent course of MF, which has an overall good prognosis if diagnosed at an early stage, as has been demonstrated in the recent literature. The information contained within this manuscript should contribute to the understanding and characterization of MF in patients in Puerto Rico.
描述波多黎各蕈样真菌病（MF）患者的人口统计学、疾病进程和治疗情况。
我们对 1999 年至 2016 年在波多黎各大学皮肤科诊所接受治疗的 MF 患者进行了回顾性病历审查。收集的数据包括人口统计学资料、诊断时的年龄、诊断时的分期、随访时间、治疗方法和研究时的分期。
1999 年至 2016 年期间共诊断出 53 例 MF 患者，平均随访时间为 89 个月。其中，45%为男性。在诊断时，40%处于 1A 期，53%处于 1B 期，7%处于 2 至 4 期。在数据收集期间，74%的患者病情稳定，18%的患者临床改善，8%的患者疾病分期进展。使用的治疗方法包括光疗、局部皮质类固醇、局部和全身维 A 酸、甲氨蝶呤、局部和全身化疗以及干扰素。
我们的研究反映了 MF 的慢性和惰性病程，如果在早期诊断，总体预后良好，这与最近的文献一致。本文所包含的信息应有助于了解和描述波多黎各患者的 MF。
