Norheim Arne Johan, Lind Andreas, Taxt Arne Michael, Nakstad Espen Rostrup, Borud Einar Kristian, Waldow Thomas
Tidsskr Nor Laegeforen. 2020 Dec 14;140(18). doi: 10.4045/tidsskr.20.0658. Print 2020 Dec 15.
Testing for SARS-CoV-2 using polymerase chain reaction (PCR) and SARS-CoV-2 antibody tests is a significant part of the effort to combat the COVID-19 pandemic. Mass testing of healthy individuals raises several issues, however, and the results can be challenging to interpret.
A healthy 19-year-old man entered the military after two weeks of quarantine. The recruit had no respiratory symptoms or fever before, during or after his enrolment, and no history of SARS-CoV-2 exposure. At enrolment, he had a positive rapid test and a venous blood sample showed antibodies against SARS-CoV-2. PCR tests of specimens obtained from the upper respiratory tract were negative at enrolment and at week three, but were positive at week six.
The overall assessment of all the tests indicates a probable asymptomatic infection. This case report illustrates the challenge of interpreting screening results in asymptomatic individuals.
使用聚合酶链反应（PCR）检测严重急性呼吸综合征冠状病毒2（SARS-CoV-2）以及SARS-CoV-2抗体检测是抗击新型冠状病毒肺炎（COVID-19）疫情工作的重要组成部分。然而，对健康个体进行大规模检测引发了若干问题，其结果也可能难以解读。
一名19岁健康男性在经过两周隔离后入伍。该新兵在入伍前、入伍期间及入伍后均无呼吸道症状或发热，也没有SARS-CoV-2暴露史。入伍时，他的快速检测呈阳性，静脉血样本显示存在抗SARS-CoV-2抗体。从其呼吸道采集的标本在入伍时及第三周的PCR检测均为阴性，但在第六周呈阳性。
对所有检测结果的综合评估表明可能为无症状感染。本病例报告说明了解读无症状个体筛查结果所面临的挑战。
