Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN, USA.
Department of Pathology Indiana University School of Medicine, Indianapolis, IN, USA.
Interv Neuroradiol. 2021 Apr;27(2):235-240. doi: 10.1177/1591019920980271. Epub 2020 Dec 15.
Carotid web is increasingly recognized as the cause of ischemic embolic strokes in younger patients. The best way to treat carotid web is debatable and carotid artery stenting (CAS) has been reported as a treatment for the carotid web in only a few case series. In this study we evaluate the safety and feasibility of CAS in symptomatic carotid webs and examined the histopathology of a carotid web.
At our institution between 2017 and 2019, 10 consecutive patients with symptomatic carotid webs were treated. We retrospectively analyzed the data for patient demographics, clinical presentation, imaging, treatment methodology and follow up.
All the patients had presented with ipsilateral embolic stroke. The mean age at presentation was 50 years (range 37-71) with seven female and three male patients. All patients underwent CAS except one patient who underwent carotid endarterectomy (CEA). In one stented patient, there was significant hypotension in the post-procedural period lasting a week. The patients were followed for a mean of 5.5 months (range one day-12 months). No recurrent stroke or transient ischemic attack (TIA) occurred. Surgical pathological studies confirmed fibromuscular dysplasia in one specimen.
In our experience CAS for carotid web is feasible and safe in patients presenting with ischemic embolic strokes.
颈动脉壁是越来越多的认识到作为缺血性栓塞性中风的年轻患者的原因。最好的方法来治疗颈动脉壁是有争议的和颈动脉支架置入术(CAS)已被报道为颈动脉壁的治疗只有少数的病例系列。在这项研究中,我们评估了 CAS 的安全性和可行性在有症状的颈动脉壁,并检查了颈动脉壁的组织病理学。
在我们的机构在 2017 年至 2019 年之间,10 例有症状的颈动脉壁患者接受了治疗。我们回顾性地分析了患者的人口统计学资料、临床表现、影像学、治疗方法和随访数据。
所有患者均出现同侧栓塞性中风。发病时的平均年龄为 50 岁(范围 37-71),女性 7 例,男性 3 例。除了一名患者接受颈动脉内膜切除术(CEA)外,所有患者均接受了 CAS。在一名支架置入患者中,术后出现持续一周的严重低血压。患者平均随访 5.5 个月(范围为 1 天至 12 个月)。无复发性中风或短暂性脑缺血发作(TIA)发生。手术病理研究证实了一例标本中的纤维肌发育不良。
根据我们的经验,对于有缺血性栓塞性中风的患者,CAS 治疗颈动脉壁是可行和安全的。