Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Indian J Ophthalmol. 2021 Jan;69(1):112-115. doi: 10.4103/ijo.IJO_1439_19.
To study the effectiveness of part-time occlusion (PTO) in different types of amblyopia in Indian population.
Prospective case series of consecutive cases of amblyopia from a tertiary care center were subjected to PTO of the better eye and monitored periodically for 6 months. Those who failed to improve by 6 months were shifted to full-time occlusion of the better eye and followed for a further 3 months.
175 eyes of 175 patients with amblyopia underwent PTO for 6 months. The mean age of the patients was 10.47 ± 4.69 years (range: 3-26 years). Major subgroups included 94 eyes with strabismic amblyopia and 70 with anisometropic amblyopia. Overall, 168 (96%) children benefited from PTO (improvement being defined as a gain of at least one line of Snellen's visual acuity). The improvement rates for strabismic amblyopes (97.9%) was significantly more than anisometropia (94.3%); P = 0.027. Of the seven patients not responding to PTO, six did not benefit even after full-time patching.
PTO is a viable and effective modality of management of amblyopia in Indian patients. Strabismic amblyopia was the commonest and responded best to the occlusion therapy in our cohort.
研究部分时间遮盖(PTO)对印度人群中不同类型弱视的疗效。
对来自三级保健中心的弱视连续病例进行前瞻性病例系列研究,对优势眼进行 PTO,并定期监测 6 个月。如果 6 个月后没有改善,则将其转为优势眼的全时遮盖,并进一步随访 3 个月。
175 例弱视患者的 175 只眼接受了 6 个月的 PTO。患者的平均年龄为 10.47 ± 4.69 岁(范围:3-26 岁)。主要亚组包括 94 只斜视性弱视眼和 70 只屈光不正性弱视眼。总体而言,168 名(96%)儿童从 PTO 中受益(改善定义为 Snellen 视力至少提高一行)。斜视性弱视者的改善率(97.9%)明显高于屈光不正性弱视者(94.3%);P = 0.027。在对 PTO 无反应的 7 名患者中,6 名即使进行全时遮盖也没有受益。
PTO 是治疗印度患者弱视的一种可行且有效的方法。在我们的队列中,斜视性弱视最常见,对遮盖治疗的反应最好。