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抗富亮氨酸胶质瘤失活 1 号抗体相关脑炎 18F-FDG PET/CT 特征及随访

18F-FDG PET/CT in Anti-Leucine-Rich Glioma-Inactivated 1 Antibody Encephalitis: Typical Pattern and Follow-up.

机构信息

From the Médecine Nucléaire, Institut Godinot.

出版信息

Clin Nucl Med. 2021 Mar 1;46(3):250-251. doi: 10.1097/RLU.0000000000003469.

DOI:10.1097/RLU.0000000000003469
PMID:33323741
Abstract

We report the case of a 55-year-old man presenting pseudopsychiatric behavior disorders of subacute-onset. MRI showed a FLAIR (fluid-attenuated inversion recovery) hyperintensity in the left hippocampus. The diagnosis of limbic encephalitis was raised, and the patient was referred for an 18F-FDG PET/CT. PET/CT depicted an increased uptake of the left mesiotemporal structures and also an increased uptake of both cerebellum and striatal areas. This pattern was compatible with an anti-leucine-rich glioma-inactivated 1 antibody encephalitis that was later confirmed.

摘要

我们报告了一例 55 岁男性出现亚急性起病的假性精神病性行为障碍。MRI 显示左侧海马体 FLAIR(液体衰减反转恢复)高信号。诊断为边缘性脑炎,并将患者转介进行 18F-FDG PET/CT 检查。PET/CT 显示左侧颞叶结构摄取增加,同时小脑和纹状体区域摄取增加。这种模式与抗亮氨酸丰富型胶质瘤失活 1 抗体脑炎相符,后来得到了证实。

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