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Flavivirus Infection and Regulation of Host Immune and Tissue Homeostasis in Insects.

作者信息

Harsh Sneh, Eleftherianos Ioannis

机构信息

Infection and Innate Immunity Lab, Department of Biological Sciences, Institute for Biomedical Sciences, The George Washington University, Washington, DC, United States.

Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, United States.

出版信息

Front Immunol. 2020 Nov 30;11:618801. doi: 10.3389/fimmu.2020.618801. eCollection 2020.

DOI:10.3389/fimmu.2020.618801
PMID:33329613
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7733989/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2f7/7733989/ee41b272545c/fimmu-11-618801-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2f7/7733989/ee41b272545c/fimmu-11-618801-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2f7/7733989/ee41b272545c/fimmu-11-618801-g001.jpg

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Mutations in ANKLE2, a ZIKA Virus Target, Disrupt an Asymmetric Cell Division Pathway in Drosophila Neuroblasts to Cause Microcephaly.ANKLE2 中的突变会破坏果蝇神经母细胞中的不对称细胞分裂途径,从而导致小头畸形。该突变是 Zika 病毒的靶点。
Dev Cell. 2019 Dec 16;51(6):713-729.e6. doi: 10.1016/j.devcel.2019.10.009. Epub 2019 Nov 14.
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Cell Rep. 2019 Nov 12;29(7):1946-1960.e5. doi: 10.1016/j.celrep.2019.10.029.
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Flavivirus infection-A review of immunopathogenesis, immunological response, and immunodiagnosis.黄病毒感染——免疫发病机制、免疫反应和免疫诊断综述。
Virus Res. 2019 Dec;274:197770. doi: 10.1016/j.virusres.2019.197770. Epub 2019 Oct 15.
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