Tait W F, Charlesworth D
Department of Surgery, University Hospital of South Manchester, United Kingdom.
Ann Vasc Surg. 1986 May;1(1):98-104. doi: 10.1016/S0890-5096(06)60709-7.
In this prospective study, the reliability of the morphologic analysis of the continuous Doppler signal was evaluated. Three parameters were considered: the maximum systolic frequency (max A), a resistance parameter (RP) and the degree of spectral broadening (SB). The apparatus used allowed us to construct a color arterial image. Seventy-four subjects were included in this study: 17 volunteers investigated by ultrasound only, and 57 patients investigated by ultrasound and arteriography. Anatomic correlation was obtained in 31 operated cases. The threshold values, as determined in the volunteers, were as follows: 3.5 kHz for max A, 0.86 for RP and 58% for SB. Sensitivity was 94% when max A, SB and cartography were combined to detect tight stenoses. The sensitivity for each of the parameters alone was much weaker (61% for max A and 33% for RP). For all carotid lesions, the sensitivity of detection when all parameters were combined was 68%. Specificity was 77%. The study of the carotid bifurcation by the continuous Doppler effect allowed us to identify tight stenosis with reliability. On the other hand, it was impossible to distinguish between normal arteries and moderate stenosis, or between tight stenosis and complete occlusion.
在这项前瞻性研究中,对连续多普勒信号形态学分析的可靠性进行了评估。考虑了三个参数:最大收缩期频率(max A)、阻力参数(RP)和频谱增宽程度(SB)。所使用的仪器使我们能够构建彩色动脉图像。本研究纳入了74名受试者:17名仅接受超声检查的志愿者,以及57名接受超声和动脉造影检查的患者。在31例手术病例中获得了解剖学相关性。在志愿者中确定的阈值如下:max A为3.5 kHz,RP为0.86,SB为58%。当将max A、SB和血管造影相结合以检测严重狭窄时,敏感性为94%。单独每个参数的敏感性要弱得多(max A为61%,RP为33%)。对于所有颈动脉病变,当所有参数相结合时,检测敏感性为68%。特异性为77%。通过连续多普勒效应研究颈动脉分叉能够可靠地识别严重狭窄。另一方面,无法区分正常动脉与中度狭窄,或严重狭窄与完全闭塞。